MiR-508-5p has been reported as a down-regulated miRNA in the primary gastric cancer tissues. However, the role of miR-508-5p on HCC has not been well elucidated. In this study, we observed that miR-508-5p was downregulated in HCC tissues when compared to the non-tumorous tissues. We...
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Prostatitis No.1 traditional chinese medicine significantly exhibited anti-inflammation role on prostatitis through miR-205-5p/YES1 Prostatitis is one common male disease with a high prevalence. Traditional Chinese medicine (TCM) has been used as an alternative method for the treatment... J Liu,Y ...
Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis. Mol. Ther. 29, 2088–2107 (2021). Article CAS PubMed PubMed Central Google Scholar Li, M. et al. Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p...
MiR-195-5p as Regulator of γ-Catenin and Desmosome Junctions in Colorectal Cancer. Int. J. Mol. Sci. 2023, 24, 17084. [Google Scholar] [CrossRef] [PubMed] Jung, H.; Kim, J.S.; Lee, K.H.; Tizaoui, K.; Terrazzino, S.; Cargnin, S.; Smith, L.; Koyanagi, A.; Jacob, ...
BCL-6 and EZH2 cooperate to epigenetically repress anti-inflammatory miR-142-3p/5p in lupus CD4+T cells lupusEZH2autoimmuneEpigenetics plays an important role in the pathogenesis of several autoimmune diseases.1,2,3 Indeed,a large body of evidence implicates abnormal T cell DNA methylation patterns...
There is compelling evidence that FoxP3+ regulatory T cells (Tregs) play a critical role in promoting tumor immune evasion. Our prior research demonstrated that the expression of miR-125b-5p directly inhibits Tregs by targeting TNFR2 and FoxP3. Given the
Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis. Mol. Ther. 29, 2088–2107 (2021). Article CAS PubMed PubMed Central Google Scholar Li, M. et al. Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p...
Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins. Di, Sun,Xu,etc.Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins.[J]... Sun,Wang...
Overexpression of circRNA circUCK2 attenuates cell apoptosis in cerebral ischemia-reperfusion injury via miR-125b-5p/GDF11 signaling. Mol Ther Nucleic Acids. 2020;22:673–83. Article CAS PubMed PubMed Central Google Scholar Vromman M, Vandesompele J, Volders PJ. Closing the circle: current...