Here, we used the monoclonal anti‐dsDNA antibody 2C10, 2‐kbp dsDNA and healthy human peripheral blood mononuclear cells (PBMCs) to test whether and how 2C10 and/or DNA cause pathology in normal cells. We found that on culture with PBMCs, 2C10 preferentially entered monocytes and that ...
Anti-Nuclear Antibody (ANA)The ANA (anti-nuclear antibody) test is a blood test that looks for antibodies that attack proteins found in the nucleus of cells.The nucleus is essentially the “command centre” or “brain” of any cell in the body. Many different types of proteins are found ...
Your doctor may order an anti-dsDNA if you have a positive antinuclear antibody (ANA) test and symptoms associated with lupus, such as persistent fatigue, pain in your joints, and a red rash resembling a butterfly across the nose and cheeks. Anti-dsDNA tests are also periodically used to a...
Article Open access 21 February 2023 New insights into the role of antinuclear antibodies in systemic lupus erythematosus Article 03 September 2020 Brief report on the relation between complement C3a and anti dsDNA antibody in systemic lupus erythematosus Article Open access 02 May 2022 Introducti...
PBMC anti-ds-DNA antibodyPBMC 的抗 ds-DNA 抗体 1.Objcetive:To research the influence of containing nourishing yin and clearing heat medicine blood serum on the SLE patient sPBMC anti-ds-DNA antibody.目的:研究滋阴清热含药血清对 SLE 患者 PBMC 的抗 ds-DNA 抗体的影响。
From this study we conclude that the value of the IIF test for ANCA detection can be greatly increased by the addition of a well standardized antigen-specific ELISA. In a significant number of patients with idiopathic small vessel vasculitis, however, the ANCA test results (either in IIF or ...
Autoimmune Diseases Working Party (ADWP) of the European Society for Blood and Marrow Transplantation (EBMT) Related terms: TLR2 Autoantibodies Monospecific Antibody Systemic Lupus Erythematosus Systemic Scleroderma Serum Amyloid A Cell Adhesion Molecule Transgenic Mouse Plasmid Vector Antinuclear Antibody ...
Zur Vereinfachung des Testablaufs und der Befun- dung unterscheidet man 2 Autoantikörper-(AAk-)Kategorien: Antikörper der Gruppe I (die meisten organspezifische AAk, ANCA, AAk gegen dsDNA) sind bereits bei einem Titer von 1:10 diagnostisch relevant, Antikörper der Gruppe II (ANA,...
To test this hypothesis, C57BL/6J mice were implanted subcutaneously with B16-Ova cells that are reconstituted with the vehicle, wild-type, or D276A mutant GSDMD and then administered intraperitoneally with an anti-PD-1 antibody or isotype IgG control (Fig. 7a). PD-1 blockade alone has no...
(evidenced by positive anti-ds DNA, positive anti-Sm, positive antiphospholipid such as anticardiolipin antibody, positive lupus anticoagulant test, or a false-positive serological syphilis test, known to be positive for at least 6 months and confirmed to be falsely positive by a negative Treponema...