antiapoptosis抗凋亡 3)anti-apoptosis gene抗凋亡基因 1.Objective To investigate the relationship between the telomerase gene and anti-apoptosis gene bcl-2 in lung cancer and in their adjacent tissues and to understand the regulation mechanism of telomerase gene and the effect of bcl-2 on telomerase...
Anti-Apaf-1(Apoptosis protease activating factor-1)(CT)凋亡蛋白活性因子-1抗体(C端)价格:价格电议产品详情:Anti-Apaf-1(Apoptosis protease activating factor-1)(CT)??凋亡蛋白活性因子-1抗体(C端) 抗原常规性... 纯度:99% 用途:仅限科研实验 不得用于临床医疗 ...
LOXL1 was found to exhibit antiapoptotic activity by interacting with multiple antiapoptosis modulators, especially BAG family molecular chaperone regulator 2 (BAG2). LOXL1-D515 interacted with BAG2-K186 through a hydrogen bond, and its lysyl oxidase activity prevented BAG2 degradation by competing ...
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 2006; 10: 389–399. Article CAS PubMed PubMed Central Google Scholar Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J et al...
αA-crystallin is a molecular chaperone and an antiapoptotic protein. This study investigated the mechanism of inhibition of apoptosis by human αA-crystallin and determined if the chaperone activity of αA-crystallin is required for the antiapoptotic fu
产品名称:anti-ASPP2(apoptosisstimulatingproteinofP532)??P53凋亡刺激蛋白2 品牌:白益 货号:BY-K1283R 详见说明书。 单克隆抗体: 解决多克隆抗体特不高的理想方法是制备识别单一表位特的抗体。如果能获得仅针对单一表位的浆细胞克隆,并使其在体外扩增分泌抗体,就有可能获得单一表位特的抗体。然而,浆细胞在体外的...
Endothelin-B receptor agonist, IRL-1620, provides significant neuroprotection following cerebral ischemia in rats. Whether this neuroprotection is due to inhibition of apoptosis is unknown. IRL-1620-treated rats following permanent middle cerebral artery
(Fig.5a). Significantly enriched genes also included those involved in apoptosis (*P = 0.047), ferroptosis (*P = 0.033) and autophagy (**P = 0.002), revealing the combinational and comprehensive cell death fate by the pathological changes34. By comparing the genetic intersections ...
BCL-2 family proteins are central regulators of mitochondrial apoptosis and validated anti-cancer targets. Using small cell lung cancer (SCLC) as a model, we demonstrated the presence of differential addiction of cancer cells to anti-apoptotic BCL-2, BCL-XLor MCL-1, which correlated with the ...
The intrinsic pathway of apoptosis is critical in both lapatinib resistance and anoikis.44 We therefore examined the association of KLFs with factors known to participate in apoptotic signaling. In response to lapatinib or trastuzumab treatment, we observed induction of not only KLF4/5 (Figures 3b ...