apoptosis; (4) Normal mature lymphocytes of PBMC could be induced to proliferate and /or to die from apoptosis when they were costimulated by anti-CD〓McAb and rIL-2. Both proliferation and apoptosis were existing in the same cultivation system sugsesting that the presence of rIL- 2 might ...
The pathogenesis of the Sjogren???s Syndrome (SjS) has not yet been completely defined. However, the cell-mediated immunity plays an important role and the apoptosis of the ductal and acinar epithelial cells is responsible of the glandular tissue damage, through the cytotoxic T-cells, particularl...
几anti-Fas :APO 1正面泡沫细胞显露接受apoptosis 相关内容 a输入序列 Input sequence[translate] aAnd it's science-based. 并且它是基于科学的。[translate] a在微氧活性污泥中存在着好氧微生物,其正常的生长代谢消耗了溶解氧,使得反应器中存在一定体积的厌氧微环境,为厌氧微生物提供了生长空间。因此,在反应器中...
but tumour cells often have faulty apoptotic pathways. These defects not only increase tumour mass, but also render the tumour resistant to therapy. So, what are the molecular mechanisms of tumour resistance to apoptosis and how can we use this knowledge to resensitize tumour cells to cancer the...
they are not directly involved in apoptosis induction45. For example, the enzyme tissue transglutaminase46, autophagy mediator Beclin-147, and transcription regulator SUFU48all possess BH3-like sequences through which Bcl-2 interactions regulate their activity. Bcl-2 and related proteins also interact...
It may also induce apoptosis by targeting the CK2α subunit, known for its role as an anti-apoptotic protein. Additionally, vanillin has the potential to inhibit MARK4, a protein that is often overexpressed in various cancers, making it a promising target for future studies. Other mechanisms ...
Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses. PLoS Pathog. 2008, 4, e1000078. [Google Scholar] [CrossRef] [Green Version] Magez, S.; Schwegmann, A.; Atkinson, R.; Claes, F.; ...
Some nanoparticles can cross the placenta into the fetus by passive diffusion or endocytosis, which can trigger fetal inflammation, apoptosis, genotoxicity, cytotoxicity, low weight, reproductive deficiency, nervous damage, and immunodeficiency, among others." - Nanoparticles and female reproductive system:...
mechanisms can be promoted through anti-apoptosis protein Bcl - 2, the expression to reduce apoptosis protein, and suppression of Expression Bax rat neuronal apoptosis, thus protecting neurons end, further improving the learning memory barriers in cognitive ability. ...
Most cell types activate pro-survival pathways and resist apoptosis when senescent [11]. They lose their cell type specific functionality and replicative potential required for tissue regeneration and acquire a senescence-associated secretory phenotype (SASP) [12]. The SASP is characterized by the ...