The structures of the various regions of an antibody molecule are analysed and correlated with biological function. The structural features which relate to potential applications are detailed.doi:10.1016/0161-5890(94)90001-9PADLAN EAMolecular Immunology...
摘要: The structures of the various regions of an antibody molecule are analysed and correlated with biological function. The structural features which relate to potential applications are detailed.关键词: Animals Humans Antibodies Crystallography, X-Ray Amino Acid Sequence Models, Molecular Molecular ...
The cardiovascular apparatus is a transport circuit that carries blood cells, oxygen and nutrients to cells of the body’s organs, and wastes produced by working cells to their final destinations (mainly lungs, liver, and kidneys). It is involved in both
ELAM, Endothelial adhesion molecule; ICAM, intercellular adhesion molecule; IL, interleukin; NO, nitric oxide; TGF, transforming growth factor; TNF, tumor necrosis factor. Pulmonary macrophages (alveolar, intravascular, and interstitial), which have an immense biologic armamentarium, are the single most...
___ are of little benefit to the cell that secretes them but alert neighboring cells from being infected interferons compliment system group of 30 or more globulins contribute to innate and adaptive immunity-- completes the action of the antibody classical...
Five crystal structures of CD1 proteins bound to lipids have now been solved. These show that the alkyl chains of antigens are inserted into a hydrophobic groove so that their carbohydrate or peptide moieties protrude for contact with T-cell receptors. ...
Myasthenia gravis (MG) is a relatively rare acquired, autoimmune disorder caused by an antibody-mediated blockade of neuromuscular transmission resulting in skeletal muscle weakness and rapid muscle fatigue. The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic ...
Neurovascular injury is often observed in traumatic brain injury (TBI). However, the relationship between mechanical forces and vascular injury is still unclear. A key question is whether the complex anatomy of vasculature plays a role in increasing forc
Cells of the Adaptive Defense System: An Overview Lymphocytes Macrophages Humoral (Antibody Mediated) Immune Response Active and Passive Humoral Immunity Antibodies Cellular (Cell-Mediated) Immune Response Lymphocyte Differentiation and Activation See also ...
The blood-brain barrier (BBB) is a selective semi-permeable membrane between the blood and the interstitium of the brain, allowing cerebral blood vessels to regulate molecule and ion movement between the blood and the brain.[1]The BBB is composed of endothelial cells (ECs), pericytes (PCs),...