The human aminopeptidase N (APN) is a ubiquitous transmembrane glycoprotein, with a large extracellular region and a small intracellular NH2-terminal membrane anchor that may lead to an arch-like arrangement on the cell surface, forming and open or a closed conformation [24]. It is a member ...
AminopeptidaseEy is a dimericenzymewith homologous subunits, each having a relative molecular mass of 150000Da[6]. It contains 1.0mol of zinc per mol of each subunit[6]. The enzyme molecule is seen as a dimer composed of two globular subunits by electronmicrographyat a magnification of 10...
1 In essence, they argued that if genes control the immune response, and if some diseases are triggered by the immune response, then those same genes might influence who receives a diagnosis of diseases like rheumatoid arthritis, systemic lupus erythematosus, or Graves’ disease. Their prediction ...
Aminopeptidase Ey is a dimeric enzyme with homologous subunits, each having a relative molecular mass of 150000Da[6]. It contains 1.0mol of zinc per mol of each subunit[6]. The enzyme molecule is seen as a dimer composed of two globular subunits by electron micrography at a magnification ...
The authors would like to thank Alun Parsons, Minna Suvela, the FIMM Sequencing Unit, the FIMM High Throughput Biomedicine Unit, and the FIMM Bioinformatics Unit for their excellent technical support. A&M Labor GmbH (Bergheim, Germany) is acknowledged for performing the aminopeptidase hydrolysis ...