EndopeptidasesSubstrate SpecificityKineticsSynaptic TransmissionMorphineCorpus StriatumThe degradation of the Met-enkephalin by peptidases present in striatum extracts was followed by a new H.P.L.C. method, base
In addition, ARTS-1 is a member of the MA clan of the M1 family of zinc metalloproteases that typically possess aminopeptidase but not endopeptidase activity. Therefore, we propose that ARTS-1 promotes IL-6Rα ectodomain shedding via an indirect mechanism, whereby ARTS-1 enzymatic activity is ...
After 60 min of incubation at 37°C, 20 μl of 0.1 mM phosphoramidon and 20 μl of aminopeptidase M solution (4 U/well) were added. Fluorescence was analyzed after another 60 min of incubation at 37°C at 460 nm, with an excitation at 355 nm on a Victor3 multilabel plate reader ...
Bonnier P, Baert JL: Identification of Cathepsin L-Like Proteinase and Aminopeptidase in Yolk Granules of the Sand Worm, Nereis-Diversicolor. Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology. 1992, 103: 425-430. Article Google Scholar Cho WL, Deitsch KW, Raikhel AS: An...
[glutamine-hydrolyzing] Q96HC4 PDLI5 PDZ and LIM domain protein 5 P13797 PLST Plastin-3 P21589 5NTD 5′-nucleotidase P15144 AMPN Aminopeptidase N P26639 SYTC Threonine—tRNA ligase, cytoplasmic Q05682 CALD1 Isoform 5 of Caldesmon P06756 ITAV Integrin alpha-V P21333 FLNA Isoform 2 of ...
serine proteases (Figure5). Interestingly, two classes of proteases appeared to be considerably expanded in comparison toEchinococcusspp.: both the M17 (amino-terminal leucyl aminopeptidases) and the serine endopeptidase classes S1A (chymotrypsin A-like) and S28 (lysosomal Pro-Xaa carboxypeptidase-...
Synuclein HH AMICA/JAML H Aminoacylase/ACY1 H Aminopeptidase N/CD13 H H Amphiregulin HM HM H H AMPK a1 HMR AMPK a1, Phospho (T183) H Amyloid b H Amyloid b aa 1–42 H Angiogenin HM H HHH KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine...
[glutamine-hydrolyzing] Q96HC4 PDLI5 PDZ and LIM domain protein 5 P13797 PLST Plastin-3 P21589 5NTD 5′-nucleotidase P15144 AMPN Aminopeptidase N P26639 SYTC Threonine—tRNA ligase, cytoplasmic Q05682 CALD1 Isoform 5 of Caldesmon P06756 ITAV Integrin alpha-V P21333 FLNA Isoform 2 of ...
The aminopeptidase was capable of degrading several peptides by hydrolysis of the N-terminal amino acid. The peptidase had no endopeptidase or carboxypeptidase activity. The aminopeptidase activity was optimal at pH 7 and 40掳C. The enzyme was completely inactivated by the p-chloromecuribenzoate ...
Besides other peptidases (neutral endopeptidase (CD10), aminopeptidase N (CD13), and dipeptidyl-peptidase IV (CD26)) carboxypeptidase M should be assigned to a cluster differentiation (CD) group. Acknowledgments We thank Dr. Frank Emmerich for providing sufficient amounts of MAX.1 and MAX.11 ...