Studies in amide hydrolysis: the acid, base and water reaction, in: The Amide Linkage (A. Greenberg, C.M. Breneman, J.F. Liebman, eds.), pp. 85–114, John Wiley & Sons, New York.Brown, R. S. Studies in Amide Hydrolysis. In The Amide Linkage; Greenberg, A., Breneman, C. M...
If desired, the ligands can be further purified by recrystallization from hot water. Dinuclear platinum complex synthesis using the bispyridine ligands is done in hot water using transplatin. The most informative of the chemical characterization techniques to determine the structure and gross purity of...
First, the results show that hydrolysis of 4'- and 2'-nitrophthalanilic acid is intramolecular catalyzed reaction in acidic solutions (pH < 4.3). The neutral species are the active forms for the intramolecular catalysis. The mass loss was observed during the hydrolysis, and a by-product N-...
The reaction of a 2-pyridylthiol ester with a dimethylaluminum amide leads to the rapid formation of the corresponding amide. The tolylthiol esters can be activated with silver trifluoroacetate and coupled even with poorly reactive amino compounds. 关键词: rhodium(II) carbenoid asymmetric synthesis ...
A process for producing an aromatic amine comprises heating an aromatic sulfonate and a metal amide in liquid ammonia in a closed reactor at a temperature of at least 40掳 C to produce a metal arylamide and reacting the resultant metal arylamide with water or lower aliphatic alcohol to ...
With toluene a 39% yield was obtained, whereas with the usage of other cosolvents like water or THF either deprotection of the TBS group or no conversion was observed. Significant yield improvements and minimization of the reaction time (7 days to 3 h) could be achieved with the assistance ...
The produced group is made to contact with water and converted to ammonium hydroxide salt under basic condition and, at the same time, the amide group is allowed to autohydrolysis. The reaction can be used for the removal of protecting group from an amino compound or the synthesis of polymer...
Besides molecular water, a similar hydrolytic effect might be produced by hydroxyl radicals (OH) generated under the ionizing action of cosmic rays. Therefore we tested the reaction of glycine amide with OH radical as well. Nevertheless, although the barrier height decreased significantly, by ca. ...
The characteristic reaction of covalent amides ishydrolysis(achemical reactionwith water), by which they are converted to acids and amines; this reaction ordinarily is slow unless it is catalyzed by a strong acid, analkali, or anenzyme. Amides also can be dehydrated to nitriles. Amides are not...
sodium nitrite, air. Can become explosive in storage. Violent reaction with dinitrogen tetraoxide. Will react with water or steam to produce heat and toxic and corrosive fumes of sodium hydroxide and ammonia. When heated to decomposition it emits highly toxic fumes of NH3 and Na2O. See also AM...