Alzheimer's disease(AD) is a most common neurodegenerative disorder, which associates with impaired cognition. Gut microbiota can modulate host brain function and behavior via microbiota-gut-brain axis, including cognitive behavior.Germ-free animals, antibiotics, probiotics intervention and diet can ...
Microbiota-Brain-Gut Axis and Neurodegenerative Diseases Quigley,Eamonn M. M. - 《Curr Neurol Neurosci Rep》 - 2017 - 被引量: 24 Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and...
近日,《Alzheimer’s& Dementia》杂志(IF:13.0)在线发表了题为“The linkbetween gut microbiome and Alzheimer's disease: From the perspective of newrevised criteria for diagnosis and staging of Alzheimer's disease”的综述,系统总结了阿尔茨海默病(Alzheimer's disease, AD)连续疾病谱的肠道菌群变化特征、肠...
Alzheimer's disease (AD) is a neurodegenerative disorder marked by neuroinflammation and gradual cognitive decline. Recent research has revealed that the gut microbiota (GM) plays an important role in the pathogenesis of AD through the microbiota-gut-brain axis. However, the mechanism by which GM ...
In this article, we reviewed the current research status of AD peripheral blood biomarkers and AD-related intestinal microbiota biomarkers, in order to provide a reference for the early diagnosis and prediction of the disease progression.阿尔茨海默病(Alzheimer’s disease, AD)是一种中枢神经退行性...
gut microbiota regulatorsanti-inflammatory drugslipid metabolism regulatorsautophagic modifierscircadian rhythm regulatorsgene and cell therapiesAs the population ages, Alzheimer's disease (AD), the most common neurodegenerative disease in elderly people, will impose social and economic burdens to the world....
Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders, such as Parkinson's disease, amyotrophic lateral sclerosis, and depression. However, whether the composition and diversity of gut microbiota is altered in patients with Alzheimer's disease (AD) remain largely unkno...
5. The blood brain barrier during aging 6. The gut microbiota in Alzheimer’s disease 7. Microbiota-gut-brain axis and TLRs: potential implications for AD 8. The potential therapeutic targets 9. Summary and outlook Declaration of Competing Interest Acknowledgements References Figures (1)Computational...
近日,Alzheimer’s & Dementia杂志(IF:13.0)在线发表了题为“The link between gut microbiome and Alzheimer's disease: From the perspective of new revised criteria for diagnosis and staging of Alzheimer's disease”的综述,系统总结了阿尔茨海默病(AD)连续疾病谱的肠道菌群变化特征、肠道菌群与AD发病机制的关...
Alzheimer’s disease; gut microbiota; microbiota–gut–brain axis; neurodegenerative disease; intestinal flora1. Introduction Alzheimer’s disease (AD), a neurodegenerative disease, as well as the most common cause of dementia in the elderly population, is a serious threat to human health and ...