Methods: We compared the clinical utility between patients who underwent amyloid-PET appropriately or inappropriately and among the subgroups of patients defined by the AIT...doi:10.1016/S0924-977X(17)31798-4Provasi, S.Ferrari, C.Festari, C....
"Our study is unique as it shows a direct causal link between gut bacteria and Alzheimer's disease. It was striking that the mice which completely lacked bacteria developed much less plaque in the brain", says researcher Frida Fåk Hållenius, at the Food for Health Science Centre. "The ...
Recently, we reported that patients with mild cognitive impairment (MCI) harbor specific signature of bacteria in their gut and that a modified Mediterranean ketogenic diet (MMKD) improves Alzheimer's disease (AD) markers in cerebrospinal fluid (CSF) and the signatures of gut bacteria. However, ...
A growing body of research suggests a correlation between Alzheimer's disease and an unhealthy gut, and Australian scientists are hoping to take this a step further by exploring how harmful gut bacteria access the brain and leads to dementia. University of South Australia nano bio-scientist Dr. ...
Cell Host and Microbe——[30.3] ① 西安交通大学吴岳、袁祖贻和团队,发现特定肠菌及其胆汁酸(BA)代谢物或可改善阿司匹林引发的肠道损伤;② 分析临床队列和小鼠模型表明,阿司匹林改变肠道菌群组成,抑制戈氏副拟杆菌(Pd)生长,并影响肠道BA池,损伤肠屏障;③ 补充Pd或其BA代谢物7-酮-LCA,可减少阿司匹林引起的肠道损...
Considerable attention has been focused on the role of gut microbiome in Alzheimer’s disease (AD) and Parkinson’s, where studies in both human cohorts and mouse models suggest a bidirectional relationship between gut bacteria and disease progression [23, 28,29,30,31]. Intentional disruption of...
The gut microbiome, i.e., the community of bacteria and other microorganisms living in the human gut, has been implicated both directly and indirectly (mediating the effects of diet) on human health [1,2]. The associations between gut microbiome composition and disease status have been widely ...
and the human gut microbiome, that is, coronary artery disease (CAD)12,41, T2D26,42, Alzheimer disease (AD)43,44and prostate cancer45,46. We utilized the population-based, multiomic FINRISK 2002 cohort47to assess the individual and combined performance of PRSs, gut microbiome scores and ...
Parkinson’s disease Alzheimer’s Schizophrenia Autism Anxiety Pain Amyotrophic lateral sclerosis Besides neurological conditions, researchers are also taking a closer look at gastrointestinal (GI) conditions and how they affect the way your brain works. ...
Indole was a tryptophan metabolite, previous research found indole supplementation reduced the activation of the NLRP3 inflammasome to suppress the neuroinflammation in Alzheimer's disease mice (Sun et al., 2022). Quinolinic acid is a tryptophan metabolite of the skin microbiota, which can inhibit ...