Alphavirus is a member of the group IV Togaviridae family of viruses that all have a positive sense single stranded RNA genome. Alphaviruses areenveloped with a 70 nm diameter, and they tend to be spherical in shape. The Alphavirus genome encodes for structural proteins Capsid protein C,...
Alphaviruses are enveloped viruses of the Togaviridae family whose genome consists of a positive-sense RNA of ~9–11kb with a 5′ cap structure and 3′ polyadenosine tail. From: Current Opinion in Virology, 2013 About this pageAdd to MendeleySet alert ...
Alphaviruses are a genus of enveloped, positive-sense, single-stranded RNA viruses belonging to theTogaviridaefamily (Kuhn2007; Strauss and Strauss1994). Alphavirus virions are approximately 70 nm in size and consist of capsid proteins surrounding a single RNA genome and two transmembrane glycoprotein...
A genus of the family of Togaviridae viruses (e.g. Eastern Equine Encephalitis virus, Western Equine Encephalitis virus) transmitted to humans by mosquito bite. Alphaviruses have a single-stranded RNA genome. Infection may cause fever, joint pains, rash, or central nervous system infection. ...
Define alphavirus. alphavirus synonyms, alphavirus pronunciation, alphavirus translation, English dictionary definition of alphavirus. Noun 1. alphavirus - an arbovirus of the family Togaviridae that can cause a variety of encephalitis in horses Togaviri
Cp binds many discrete sites across the genome Fig. 2: Cp’s genomic RNA-binding sites in cells. Full size image Analysis of the nucleotide composition of Cp’s top 58 binding sites revealed that these sequences were relatively U-rich and A-poor (Supplementary Fig.2a). In contrast, sequen...
The positive sense alphavirus genome is translated to produce four non-structural proteins (nsP1–nsP4) that comprise the viral replication complex. A subgenomic RNA is also produced which encodes the five structural proteins (C, E3, E2, 6K, and E1) functioning in the assembly of progeny ...
Alphavirus genome map. The position of the -1 ribosomal frameshift site is indicated. Nucleotide coordinates are for SFV ([GenBank:NC_003215]; 11442 nt). Full size image The 6K protein is a small, hydrophobic, cysteine-rich, acylated protein, involved in envelope protein processing, membrane ...
The exact mechanism by which Rin/G3BP enhances viral replication in both vertebrates and invertebrates is still unknown; however, G3BPs are not directly involved in the translation of incoming genomes, nor in genome replication. Perhaps G3BPs support the switch between viral nonstructural poly...
Viruses typically form icosahedral shells or helical tubes by repeating a capsomere (made up of one or a few protein subunits) in a structured design to protect their genome and form an active virion [1]. Each copy of the capsomere has the same shape and they tile [2] across the shell...