Alpha-ketoglutarate (KG) is a crucial metabolite in all living organisms, as it participates in a variety of biochemical processes. We have previously shown that this keto acid is an antioxidant and plays a key role in the detoxification of reactive oxygen species (ROS). In an effort to ...
Alpha-ketoglutarmate, glutamate antagonism and GABA depletion--clues to the pathogenesis of hepatic encephalopathy? 来自 NCBI 喜欢 0 阅读量: 20 作者:T Kardel,CH Gips 摘要: Kardel T, Gips CH.被引量: 85 年份: 1974 收藏 引用 批量引用 报错 分享 ...
Alpha-ketoglutarate (AKG) is an intermediate of the Krebs cycle which bridges amino acid metabolism with glucose oxidation in animals. Of particular interest is the conversion of AKG into glutamate by mitochondrial glutamate dehydrogenase in the gastrointestinal tract where glutamate has multiple physiologi...
In order to provide evidence relevant to the hypothesis that nonsynaptically derived alpha-ketoglutarate serves as a metabolic precursor of the neurotransmitter pools of glutamate and GABA the uptake and metabolism of alpha-ketoglutarate by nerve terminal enriched material was studied and compared to cor...
An anion of α-ketoglutaric acid, alpha-ketoglutarate (AKG), is an intermediate of tricarboxylic acid (TCA) cycle as well as nitrogen and amino acid metabolism (Fig. 1). Oxidative decarboxylation of isocitrate in the TCA cycle and oxidative desamination of glutamate are main sources of AKG i...
英文名称α-Ketoglutaric acid 应用A derivative of glutaric acid. 储存温度2-8°C储存 运输条件冰袋运输 作用类型激动剂 作用机制氧化谷氨酸受体激动剂 产品介绍 2-Ketoglutaric Acid is a derivative of glutaric acid and is an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on ...
英文别名 Pentanedioic acid, oxo- | 2-ketoglutaric acid | 4qkd | ALFA-KETOGLUTARIC ACID | keto glutaric acid | 2-ketoglutarate | alpha Ketoglutarate | alpha-Ketoglutaricum acidum | CAS-328-50-7 | NCGC00090946-01 | NCGC00013225-04 | 4nro | DTXCID3013179 | AS-12579 | bmse000801 | bmse...
A coryneform L-glutamate producing bacterium deficient in alpha -ketoglutaric dehydrogenase activity; a process for producing L-glutamic acid by using the bacterium; a gene coding for an enzyme having an alpha -KGDH activity originating in the coryneform L-glutamate producing bacterium; a recombinant ...
(a) Sequencing traces representative of each of the five unique mutations found in DLBCL; arrows indicate the nucleotide change, and amino acid substitution is listed at the bottom. Constitutive DNA was available from two patients with D2HGDH mutant tumours (R212W variant), and one case is ...
Alpha-ketogluterate (AKG) is known to be a key intermediate in the Kreb's Cycle for the production of energy. AKG is a precursor of glutamate and glutamine and can play a role in muscle recovery, cellular energy, and can support healthy...