The invention relates to a pharmaceutical composition comprising alpha-ketoglutarate, optionally a glutamate dehydrogenase, and optionally a cofactor for glutamate dehydrogenase. The composition according to the invention is particularly useful for the treatment or prevention of a liver disease, wherein the...
Alpha-ketoglutarate (AKG) is an intermediate of the Krebs cycle which bridges amino acid metabolism with glucose oxidation in animals. Of particular interest is the conversion of AKG into glutamate by mitochondrial glutamate dehydrogenase in the gastrointestinal tract where glutamate has multiple physiologi...
Alpha-ketoglutarate (AKG) is an intermediate of the Krebs cycle which bridges amino acid metabolism with glucose oxidation in animals. Of particular interest is the conversion of AKG into glutamate by mitochondrial glutamate dehydrogenase in the gastrointestinal tract where glutamate has multiple physiologi...
英文名称:L-Arginine alpha-Ketoglutarate(2:1) 外观:白色粉末 重金属:0ppm CAS编号:5256-76-8 别名:5256-76-8 纯度:98% 分子式:C17H34N8O9 用途:(1)促进和扩张肌肉运动;(2)促进肌肉的快速增长和恢复;(3)增强力量和精力。 武汉鑫伟烨化工有限公司生产厂家在线QQ:359501377 电话027-59216377/18502781673 ...
Consideration was therefore given to the possibility that glutamic acid might be supplied through transamination of another metabolic intermediate after its entry into the erythrocyte. This communication gives data indicating that α-ketoglutarate, the most obvious possibility, can be incorporated into ...
Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle determining the overall rate of the citric acid cycle of the organism. It is a nitrogen scavenger and a source of glutamate and glutamine that stimulates protein synthesis and inhibits protein degradation in muscles. AKG as a precur...
Alpha‐ketoglutarate administered to the piglets after prenatal influence of dexamethasone lowered the total cholesterol concentration by 40%, and enhanced aspartate by 41%, serine by 76%, glutamate by 105%, glutamine by 36%, glycine by 53% and arginine by 105%, as well as methionine and ...
alpha-Ketoglutarate (a-KG) is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Anaplerotic reactions replenish the cycle by synthesizing a-KG from transamination of glutamate, or through the action of glutamate dehydrogenase. a-KG is an important nitrogen tra...
Age-related osteoporosis is characterized by the deterioration in bone volume and strength, partly due to the dysfunction of bone marrow mesenchymal stromal/stem cells (MSCs) during aging. Alpha-ketoglutarate (αKG) is an essential intermediate in the tricarboxylic acid (TCA) cycle. Studies have re...
[4].STOLLB,MCNELLYS,BUSCHERH P,etal.Functionalhepatocyte heterogeneity in glutamate,aspartate andα-ketoglutarate uptake: a histoautoradiographical study[J].Hepatology,1991,13(2) : 247-253. [5].KRISTENSENN B,JUNGVIDH,FERNANDEZJ A,etal.Abs...