Glutamate and alpha-ketoglutarate: key players in glioma metab- olism. Amino Acids 2017;49(1):21-32.Maus A, Peters GJ. Glutamate and α-ketoglutarate: key players in glioma metabolism. Amino Acids. 2017;49(1):21-32. https://doi.org/10.1007/s00726- 016-2342-9....
The present results are analogous to evidence indicating a requirement of high-energy compounds generated by the respiratory chain for a maximal rate of dismutation between malate and alpha-ketoglutarate plus ammonia except that here a h... L Danielson,L Ernster - 《Biochemical & Biophysical Researc...
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Dietary supplementation with glutamate precursor a-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs. Amino Acids 2015;47:1309-18.Dietary supplementation with glutamate precursor alpha-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs. Wang L,Hou Y,Yi ...
Malaria parasites uses GDH as crucial enzyme to obtain energy via Krebs cycle, where it oxidizes glutamate to alpha-ketoglutarate utilizing NADP and releasing NADPH during intraerythrocytic stage10. GDH is approximately 50–60 kDa sized metabolic soluble protein11,12. InP. falciparumthreegdhgenes en...
In isotopic experiments, the labeling pattern of glutamate opens a window on hepatic metabolism, particularly the citric acid cycle, gluconeogenesis and fatty acid oxidation. This is because glutamate is in isotopic equilibrium with alpha-ketoglutarate, whose labeling pattern is influenced by the followin...
Alpha-ketoglutamate (α-KG) reductive amination activity in rat brain was found to be mostly absorbed with an antibody against liver glutamate dehydrogenase. With this and anti-glutamine synthetase antibodies, α-KG reductive amination activity was immunocytochemically shown to coexist with glutamine syn...
Tet3 is the main α-ketoglutarate (αKG)-dependent dioxygenase in neurons that converts 5-methyl-dC into 5-hydroxymethyl-dC and further on to 5-formyl- and 5-carboxy-dC. Neurons possess high levels of 5-hydroxymethyl-dC that further increase during neura
Since it can be synthesized from alpha-ketoglutarate, dietary intake of Glu is not necessary as long as enough total protein is available. Healthy individuals absorb amino acids and proteins in the proximal small intestine nearly completely. Food proteins are hydrolyzed by an array of gastric, ...
Since it can be synthesized from alpha-ketoglutarate, dietary intake of Glu is not necessary as long as enough total protein is available. Healthy individuals absorb amino acids and proteins in the proximal small intestine nearly completely. Food proteins are hydrolyzed by an array of gastric, ...