alpha-ThalassemiaAlpha‐thalassemiaAlpha‐globin geneThalassemia mutationsHb Bart'sHbHClinical test for alpha Thalassemia offered by Burc Genetics Diagnostic CenterSensagent
Synonyms HBA1, Hemoglobin a, HBA2, Alpha-globin, Alpha globin Calculated Molecular Weight 15 kDa GenBank Accession Number BC050661 Gene Symbol HBA1 Gene ID (NCBI) 3039 Conjugate Unconjugated Form Liquid Purification Method Protein A purification UNIPROT ID P69905 Storage Buffer PBS Only Storage ...
Since the Iranian populaion is a mixture of different ethnic groups, frequency and distribution of globin mutations in various regions of the country need to be clarified. The aim of this study was to determine the common alpha globin gene deletions among individuals with hypochromic microcytic ...
Alpha-globin gene triplicationThe simultaneous presence of a heterozygous β-thalassemia with α-gene triplication may cause anything from a thalassemia trait to thalassemia intermedia of mild to moderate severity. An 8-month-old ethnic Gypsy male infant with failure to thrive from birth, mild ...
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slight...
In order to determine whether any heterogeneity exists in the human α-globin chain, i.e. whether the products of the duplicated genes are identical, we have determined the total sequence of 14 α-globin chains: seven of these were abnormal, while six were normal chains from the same ...
1. ␣-globin gene cluster and deletions associated with ␣° (A) and ␣ϩ (B) thalassemia. Hb Bart hydrops fetalis syndrome is the most severe -alpha- thalassemia clinical condition. Usually, it is associated with the absent function of all four alpha globin genes (- -/- -). ...
HBA1, Hemoglobin a, HBA2, Alpha-globin, Alpha globinOverview Tested Applications Product Information Print datasheet MSDS Validation Data Gallery Filter: AllSandwich ELISASample testCytometric bead arrayAffinity Sandwich ELISA standard curve of MP00239-3 Sandwich ELISA standard curve of MP00239-3, Hu...
5). Clinically, this model is most similar to a trans-two alpha gene deletion, in which only one of the two copies of the alpha globin gene is lost. However, this genetic deletion only affects alpha globin expression in the endothelium. Endothelial-specific deletion was confirmed, with no ...
Reactivity human Applications Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test Conjugate Unconjugated CloneNo. 240049D2 Review Product Cat no : 83185-3-PBS Synonyms HBA1, Hemoglobin a, HBA2, Alpha-globin, Alpha globinOverview...