α1,4- N -acetylglucosaminyltransferase (α4GnT) is a glycosyltransferase that mediates transfer of GlcNAc from UDP-GlcNAc to βGal residues with α1,4-linkage preferentially present in O -glycans forming GlcNAcα1→4Galβ→R, and cDNA encoding α4GnT was isolated from a human stomach cDNA...
A cyclodextrin glycosyltransferase (CGTase) was successfully used for the preparation of benzyl and phenyl α-d-glucopyranoside derivatives.3062 The production of glycosides with the CGTase of Brevibacterium species has been patented.3063 Using an alkalophilic CGTase in a slurry containing 13% sucrose ...
the mechanism of action of 4-α-glycosyltransferase (4α-Gtase) needs to be further elucidated. In addition, gene modification of 4α-Gtase can be carried out to improve its specificity and activity. The large molecular ring in LR-CDs is relatively flexible, which means that some guest mol...
Chatterjee SK, Bhattacharya M, Barlow JJ (1979) Glycosyltransferase and glycosidase activities in ovarian cancer patients. Cancer Res 39:1943–1951 Chen D, Liu JL, Liu Y, Zhu J, Wang SW (2011) Lack of an association between -308G>A polymorphism of the TNF-α gene and liver cirrhosis ri...
The products generated by Golgi-localized GalAT were converted by endopolygalacturonase treatment to mono- and di-galacturonic acid, thereby showing that GalAT synthesizes 1鈫 4-linked 伪-D-galacturonan. Our data provide the first enzymatic evidence that a glycosyltransferase involved in HGA ...
WbwB is the final glycosyltransferase in the biosynthesis pathway of the ECO104 antigen repeating unit. This work contributes to knowledge of the biosynthesis of bacterial virulence factors.Czuchry, DianaSzarek, Walter A.Brockhausen, InkaQueens Univ Dept Biomed &Glycoconjugate journal...
A homology model of alpha-1,3-galactosyltransferase (alpha-1,3-GalT), the retaining enzyme responsible for the formation of alpha-galactosyl epitopes, has been developed by means of molecular modeling using the SpsA glycosyltransferase structure. A protein-ligand docking approach was used to model ...
a glucan binding domain and a second catalytic domain in the carboxylic part of the glycosyltransferase, and said glycosyltransferase being encoded by an isolated nucleic acid, said nucleic acid comprising, : i) two nucleic acid sequences encoding said catalytic domains, said nucleic acid sequences ...
doi:10.1007/978-4-431-54240-7_87α1,4- N-acetylglucosaminyltransferase (α4GnT) is a glycosyltransferase that mediates transfer of GlcNAc from UDP-GlcNAc to βGal residues with α1,4-linkage preferentially present in O-glycans forming...Nakayama, Jun...
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase.doi:10.1007/978-3-642-61117-9_38Dietmar Schomburg...