Alpha-1,4-N-Acetylglucosaminyltransferase 4, also known as A4GNT is a 45 kDa glycoprotein, member of the glycosyltransferase 32 family of proteins. A4GNT catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. A4GNT is a single-pass type II membrane protein...
DBA-reactive glycan (also called Sd(a) antigen) is a non-Gal polysaccharide antigen produced by glycosyltransferase. An enzyme, β1, 4N-acetylgalactosaminyl transferase 2 (β4GalNT2), is found to be essential for the expression of the glycosyltransferase and the subsequent glycan synthe...
This mini-review focuses on the unique properties, enzymatic production, and food applications of α-cyclodextrin, as well as its differences with β- and γ-cyclodextrins. The fermentative production of α-cyclodextrin glycosyltransferase (α-CGTase) is also discussed. More efficient processes for the...
Polycomb Group (PcG) proteins organize chromatin at multiple scales to regulate gene expression. A conserved Sterile Alpha Motif (SAM) in the Polycomb Repressive Complex 1 (PRC1) subunit Polyhomeotic (Ph) has been shown to play an important role in chrom
Biosynthesis of mixed-linkage β-glucan in strains with elevated levels of c-di-GMP requires c-di-GMP binding glycosyltransferase BgsA and putative export protein BgsB (Figure 3). It contributes to cell aggregation and biofilm formation and is required for efficient attachment to plant roots (Pere...
The PhAEV1 genome, 12,820 nucleotides (nt) in length, was predicted to encode a single large polyprotein with the catalytic core domain of viral (superfamily 1) RNA helicase (HEL, amino acid [aa] positions 1,287-1,531), glycosyltransferase (GT, aa positions ca. 2,800-3,125), and ...
Analysis of the polyprotein sequence revealed the presence of four conserved functional domains (in order from the N- to C-terminus): viral helicase 1, peptidase _C97, glycosyltransferase_GTB-type, and viral RNA-dependent RNA polymerase (RdRP). The LbEV1 polyprotein showed the highest amino ...
the mechanism of action of 4-α-glycosyltransferase (4α-Gtase) needs to be further elucidated. In addition, gene modification of 4α-Gtase can be carried out to improve its specificity and activity. The large molecular ring in LR-CDs is relatively flexible, which means that some guest mol...
Ribophorin-1 (dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1, EC 2.4.1.119, 607aa) catalyzes the transfer of a high mannose oligosaccharide to an asparagine residue as does ribophorin 2 (631aa). riboprobe Somewhat casual term for an RNA segment used to probe for...
Like other sialyltransferases, ST6GalNAc-I exhibits type II membrane protein topology and is classified into CAZy glycosyltransferase family 29 (Coutinho et al. 2003).doi:10.1007/978-4-431-54240-7_144Shuichi TsujiInstitute of Glycoscience, Tokai UniversityShou Takashima...