This raised the possibility that the DRw10 haplotype, and most probably one or more specific conformations encoded by the DR beta chain, are involved in the definition of the disease susceptibility phenotype. 展开 关键词: Cell Line Humans DNA Antibodies, Monoclonal HLA-D Antigens HLA-DR Antigen...
Evaluation of different types of milk proteins-derived epitopes using in-silico tools: a primarily study to propose a new definition for bioactive peptides Besides, to predict T cell epitopes, the major histocompatibility complex I (MHC-I) and MHC-II alleles that were more abundant among Iranian...
In contrast, the genetic linkage of HLA class I genes can also explain the statistical strength of HLA-C allele; the gene encoding HLA-C is located close to the HLA-B gene on the HLA class I genomic map (chromosome 6p)44. This linkage indicates that patients with HLA-C mismatch are mo...
To evaluate the role of complex alleles, with two or more mutations in cis position, of the cystic fibrosis transmembrane conduc- tance regulator (CFTR) gene in the definition of the genotype-phenotype relationship in cystic fibrosis (CF), and to evaluate the functional significance of the highly...
By design, the proposed method does not adjust non-polymorphic signals ({θ ij }) or total CNs ({C ij }), neither for SNPs nor for non-polymorphic CN loci - it corrects only for systematic effects in the tumor allele B fractions ({β Tj }), which by definition exist only for SNPs...
Dan Cook. Nucleic acids containing one or more carbocyclic sugars are also included within the definition of nucleic acids (Jenkins et al. (1995) Chem. Soc. Rev. pp 169-176). Several nucleic acid analogs are also described in, e.g., Rawls, C &E News Jun. 2, 1997 page 35. These ...
Identification of novel MHC class I sequences in pig-tailed macaques by amplicon pyrosequencing and full-length cDNA cloning and sequencing Pig-tailed macaques ( Macaca nemestrina ) provide important animal models in biomedical research, but utility of this species for HIV and other disease pat......
Definition of Transplantation-Related Events The occurrence of aGVHD was evaluated according to grading criteria in patients who survived more than 8 days after transplantation, and chronic GVHD (cGVHD) according to the criteria in patients who survived more than 100 days after transplantation as descri...
Definition of nonpermissive HLA combinations We defined the nonpermissive HLA allele combination as a significant risk factor for severe aGVHD, because severe aGVHD was a solid marker for alloreactivity in HSCT and was the main contributor to transplantation-related mortality.15,16 Definition of hydrop...
Plant breeding begins with the analysis and definition of problems and weaknesses of the current germplasm, the establishment of program goals, and the definition of specific breeding objectives. The next step is selection of germplasm that possess the traits to meet the program goals. The goal is...