The alkylation reaction kinetics of a series of amines of different structures by dimethyl phosphite have been studied. Two-parameter correlation equations have been deduced, relating reactivity to steric and inductive effects of substituent s attached to the nitrogen atom in the amine; a Swain-Scott...
Figure 6:N-alkylation of (hetero)aromatic amines using (hetero)aromatic and aliphatic alcohols. (a) General reaction conditions: aniline derivative (1 mmol), benzyl alcohol (1.2 mmol),1(3 mol%),t-BuOK (0.75 equiv.) and toluene (2 ml), 80 °C, 24 h. (b) Conversio...
The characteristics and advantages of the alkylation process for FCC gasoline desulfurizisation are introduced. 综述了FCC汽油烷基化脱硫的特点与优势。 www.chemyq.com 10. In organic synthesis, mono-alkylation of amines is an important kind of reaction. 伯胺的单烷基化在有机合成过程中是非常重要的一类...
Tandem β-Alkylation−α-Arylation of Amines by Carbolithiation and Rearrangement of N-Carbamoyl Enamines (Vinyl Ureas) 来自 ACS 喜欢 0 阅读量: 28 作者: Jonathan Clayden*, Morgan Donnard, Julien Lefranc, Alberto Minassi and Daniel J. Tetlow ...
A new effective catalytic system consisting of [Cp*IrCl2]2/K2CO3 (Cp*=pentamethylcyclopentadienyl) for the N-alkylation of primary amines with alcohols has been developed. As an example, the reaction of aniline with benzyl alcohol in the presence of [Cp*IrCl2]2 (5.0 mol%Ir) and K2CO3 ...
By the reaction of amines with alkylborane reagents in the presence of a catalytic amount of copper(II) acetate Cu(OAc)(2) and di-tert-butyl peroxide, a cross-coupling reaction proceeded and alkylated amines were obtained in good to excellent yields. Phenols are also applicable for this react...
Unfortunately, most of these materials need drastic reaction conditions (250–500 °C) making them not suitable for the synthesis of more advanced amines, especially life science products such as pharmaceuticals. However, in this field the use of amines is immense, and most of the drugs known ...
In organic synthesis, mono -alkylationof amines is an important of reaction. 伯胺的单烷基化在有机合成过程中是非常重要的一类反应. 互联网 Cesium carbonate catalyzed O -alkylationof phenol to synthesize alkly aryl ethers. 摘要研究了碳酸铯催化酚与卤代烃反应制备烷基芳醚. ...
Intermolecular N-alkylation of amines under conditions of the Mitsunobu reaction: A new solid-phase synthesis of tertiary benzylamines Support-bound secondary aliphatic amines can be N-benzylated with benzyl alcohols under the standard conditions of the Mitsunobu reaction if the amine is c... F Zar...
The characteristics and advantages of the alkylation process for FCC gasoline desulfurizisation are introduced. 综述了FCC汽油烷基化脱硫的特点与优势。 www.chemyq.com 10. In organic synthesis, mono-alkylation of amines is an important kind of reaction. 伯胺的单烷基化在有机合成过程中是非常重要的一类...