Neutral Single Cell Gel ElectrophoresisAntimutagensWe investigated the in vitro activity of 8 chemicals of pharmaceuticals and alimentary interest by using both the alkaline and the neutral version of the Comet assay (Single Cell Gel Electrophoresis, SCGE). Aspirin (ASA), eugenol, (EUG), paracetamol...
In summary, a comparison of dose-responses determined by the γH2AX foci and the alkaline and neutral comet assay revealed both similarities and differences. The most striking difference was the inability of the alkaline and the neutral comet assay to identify mitomycin C as a genotoxicant, while...
Comet assay gain its popularity because it is a fast and relatively easy-to-perform method for assessing damages in DNA. The two persisting variants of the method: alkaline and neutral, lead to some doubts which one would be suitable for a certain purpose. Here we present a comparison ...
Sprague DawleycyclophosphamidebleomycinIn this article we decide to evaluate genotoxic effect of the cyclophosphamide and bleomycin in the individual cells by means of alkaline comet assay using the Sprague Dawley rats in both sexes as experimental biomodel. Which were formed 5 experimental groups per ...
Assessment of chemotherapy-induced DNA damage in peripheral blood leukocytes of cancer patients using the alkaline comet assay. Terat Carc Mutag. 2002; 22 (1):13–30.↵ Kopjar N , Garaj-Vrhovac V , Milas I . Assessment of chemotherapy-induced DNA damage in peripheral blood leukocytes of ...
CometAssay Alkaline Control Cells 英文别名: CometAssay Alkaline Control Cells 中文名: 中文别名: CBNumber: CB315318124 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 CometAssay Alkaline Control Cells化学性质 安全信息 CometAssay Alkaline Control Cells性质、用途与生产工艺 ...
网络碱性彗星试验 网络释义 1. 碱性彗星试验 彗星试验,Comet... ... ) modified comet assay 改良彗星试验 )alkaline comet assay碱性彗星试验) Comet Assay 彗星实验 ... www.dictall.com|基于5个网页
两种常见的彗星实验检测方式。碱性处理&中性处理:①Alkaline CometAssay:在碱性处理条件下,DNA发生变性,因而可检测包括单链及双链断裂在内的所有DNA 损伤;②Neutral CometAssay:在中性处理条件下,DNA 维持双链构象,因而仅可以检测双链断裂。独特的优势:1、彗星分析的开创者,众多文章验证。2、多种彗星玻片样式可供...
The comet assay is a sensitive method for detection of DNA strand breaks induced by several phenomena such as direct DNA damage or incomplete excision repair [1], [2], [3], [4], [5], [6]. This test can also be used to detect and quantify DNA fragmentation occurring during apoptosis ...
1) standard alkaline comet assay 碱性彗星电泳2) comet assay 彗星电泳 1. Current status of detecting damaged DNA in single cell by comet assay; 彗星电泳检测细胞DNA损伤应用新进展 2. Human hepatocyte L02 cells were irradiated by the carbon ion beam with LET of 30 keV/μm and DNA strand ...