Aldosterone-Producing AdenomasVania Nosé MD, PhDDiagnostic Pathology: Endocrine (Second Edition)
1.Expression of aldosterone synthesis related enzyme and associated regulatory factor genes in aldosterone-producing adenoma醛固酮瘤中醛固酮合成相关酶与相应调节基因表达的变化 2.Adrenal-sparing Surgery in Patients with Aldosterone-Producing Adenomas保留肾上腺手术治疗醛固酮瘤的可行性 3.One case of severe nephro...
Aldosterone-Producing Adenomas aldosterone-producing cells clusters aldosterone regulating genes in adrenals from Caucasian patients without defined hypertension status. Objective Determine the frequency and somatic mutation status of APCCs 站内活动
Adrenal aldosterone-producing adenomas (APAs) constitutively produce the salt-retaining hormone aldosterone and are a common cause of severe hypertension. ... UI Scholl,G Goh,St?lting, Gabriel,... - 《Nature Genetics》 被引量: 405发表: 2013年 Medical management of aldosterone-producing adenomas....
33. Fallo F, Barzon L, Biasi F, Altavilla G, Boscaro M, Sonino N: Zona fasciculata-like histotype and aldosterone response to upright posture are not related in aldosterone-producing adenomas. Exp Clin Endocrinol Diabetes 1998; 106: 74–78. 34. Magill SB, Raff H, Shaker JL, et al: ...
New research has identified somatic mutations that lead to increased aldosterone production in aldosterone-producing cell clusters (APCC), which are found in normal adrenal glands. However, the spectrum of mutations differs from that found in aldosterone-producing adenomas (APAs) and indicates that APCC...
Medical Management of Aldosterone-Producing Adenomas No data are available on the long-term medical management of aldosterone-producing adenomas.To demonstrate the efficacy of medical management of aldosteron... RP Ghose,PM Hall,EL Bravo - 《Annals of Internal Medicine》...
ins and outs of aldosterone-producing adenomas of the adrenal from channelopathy to common curable cause of hypertension downloaded from MJ Brown 被引量: 0发表: 2017年 Ins and outs of aldosterone-producing adenomas of the adrenal: From channelopathy to common curable cause of hypertension Until ...
Richard Lifton and colleagues identify somatic and germline mutations in the CACNA1D calcium channel gene in aldosterone-producing adenomas and primary aldosteronism. Their functional studies show that these mutations result in channel activation at more
Sodium/potassium-transporting ATPase (NKA) are more highly expressed in aldosterone-producing adenomas (APA) with an ATP1A1 mutant to compensate for the loss of NKA pump function. This, subsequently, results in enhanced cell signaling function, including that of cell proliferation and intracellular ...