48 year old African American female was referred to endocrinology for right adrenal incidentaloma which was found by abdominal ultrasound. She complained of gaining weight of about 20 kg in 8 months, fatigue, depression, chronic diffuse abdominal pain with history of bilateral kidney stones. She ...
Article: Aldosterone-secreting adrenal adenoma as part of multiple endocrine neoplasia type 1 (MEN1): loss of heterozygosity for polymorphic chromo
Aldosterone-secreting adrenal adenoma as part of multiple endocrine neoplasia type 1 (MEN1): loss of heterozygosity for polymorphic chromosome 11 deoxyribo... A 63-year-old female presented with the extremely rare occurrence of an aldosterone-secreting adrenocortical adenoma as part of the syndrome ...
A 63-year-old female presented with the extremely rare occurrence of an aldosterone-secreting adrenocortical adenoma as part of the syndrome of multiple endocrine neoplasia type 1 (MEN1). Only two other MEN1 patients were reported in the literature with hyperaldosteronism. The patient's MEN1 syndr...
19. McLeod MK, Thompson NW, Gross MD, Grekin RJ: Idio- pathic aldosteronism masquerading as discrete aldosterone- secreting adrenal cortical neoplasms among patients with primary aldosteronism. Surgery 1989; 106: 1161–1168. 20. Gordon RD, Stowasser M, Rutherford JC: Primary aldo- steronism: are...
In conclusion, we present this case to emphasize that an adrenal adenoma might be capable of secreting both aldosterone and cortisol without clinical features of Cushing syndrome. Therefore, the screening test for Cushing syndrome should be performed in pa- tients with primary aldost...
www.nature.com/scientificreports OPEN Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing received: 01 October 2015 adenoma after adrenalectomy:accepted:08January2016 Published:17February2016 prospective study of 102 patients Che-Wei Liao1, Lian-Yu ...
Aldosterone-secreting adrenal cortical adenoma in an 11-year-old child and collective review of the literature We report a rare case of primary hyperaldosteronism due to a unilateral adrenal cortical adenoma in an 11-year-old female patient. The patient presented wi... JT Li,SCS Chi - 《Europe...
The presence of an aldosterone- and cortisol-co-secreting adrenocortical tumor should be considered if a patient has i) PA and an adenoma that is larger than 2.5cm, ii) cortisol that is non-suppressible with overnight low-dose dexamethasone, or iii) grossly elevated serum levels of hybrid ...
The low prevalence of mutations in APAs compared to NHPAs or CPAs could reflect the low number of ZG cells expressing CYP11B2 in normal adrenal gland. It is unknown if carcinomas of the adrenal cortex evolve in an adenoma-to-carcinoma sequence46. Evidence in favor of this hypothesis comes...