王婉婷,许颖,邵命海.中药单体靶向PI3K/Akt/mTOR信号通路防治糖尿病肾病的研究进展[J].上海中医药杂志,2023,57(10): 83-88. WANG W T,XU Y,SHAO M H.Research progress in monomers of traditional Chinese herbal medicine targetin...
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[2].https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-alpelisib-metastatic-breast-cancer [3].Dong C, Wu J, Chen Y, Nie J, Chen C. Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer. Front Pharmacol. 2021 Mar 15;12:628690. [4].J Can...
文献出处: He PK, Gao YY, Lyu FJ, et al. αIdebenone-Activating Autophagic Degradation of -Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson's Disease: A Network Pharmacological Approach[...
18、 pathway plays an important role in cancer stem cell self-renewal and resistance to chemotherapy or radiotherapy, which is believed to be the root of treatmentfailure and cancer recurrence, as well as metastasis.癌症中的PI3K-mTOR信号途径Figure 1 | Minding your Ps: the PtdIns(4,5)P2 PtdIn...
relationshipsbetweenhypoxia?induciblefactor?1andPI3K/Akt/mTORsignalingpathway. Keywords:hypoxiainduciblefactor?1;ph0sphatidylin0sit0l一3kinase;proteinkinaseB;mammaliantargetof rapamycin;signaltransduction 缺氧诱导因子1(hypoxiainduciblefactor1,HIF一1)
英文题目:α-Cyperone inhibits the proliferation of human cervical cancer HeLa cells via ROS-mediated PI3K/Akt/mTOR signaling pathway. 期刊杂志:European Journal of Pharmacology 影响因子:3.623 原文链接:https://sci-hub.ren/10.1016/j.ejphar.2020.173355 ...
Recent data suggests that the PI3K-AKT-mTOR signaling pathway plays an important role in cancer stem cell self-renewal and resistance to chemotherapy or radiotherapy, which is believed to be the root of treatment failure and cancer recurrence, as well as metastasis. 癌症中的PI3K-mTOR信号途径 ...
[关键词] PI3K/Akt/mTOR 信号通路;巨噬细胞;自噬;易损斑块[中图分类号] R363 [文献标志码] A doi:10. 3969/j. issn. 1000-4718. 2013. 03. 002Roles of PI3K/Akt/mTOR signaling pathway in macrophage autophagyand atherosclerotic plaque instabilityWANG He-feng 1 ,ZHAI Chun-gang 1 ,PANG Wen-...
2024年1月保定市第一中心医院耿红玉教授团队于《Int Immunopharmacol》(IF=5.6)杂志上发布了文章:Sivelestat ameliorates sepsis-induced myocardial dysfunction by activating the PI3K/AKT/mTOR signaling pathway,本研究旨在探讨西维来司他钠在脓毒症诱导心肌功能障碍(SIMD)中的作用机制。结果显示:西维来司他钠在体内...