D. et al. The role of metastasis-associated protein 1 in prostate cancer progression. Cancer Res. 64, 825–829 (2004). 29. Higashijima, J. et al. Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer. Oncol. Rep. 26, 343–348 (...
Intraductal carcinoma of the prostate (IDC-P) is a subtype of prostate cancer featured by poor prognosis. Previous studies suggested IDC-P could have a potentially unstable genome. Homologous recombination deficiency (HRD) score is a result-oriented method to describe the genomic instability status....
“BMI, a measure of overall obesity, has been associated with a higher risk of advanced prostate cancer and poorer prognosis after diagnosis. Waist circumference, a measure of central adiposity, has been associated with a higher risk of advanced and high-grade prostate cancer in some, but not ...
have a special constitutional change in gene nbs1.the invention includes a new diagnostic method for wykrywaj\\u0105c\\u0105 predisposition to aggressive prostate cancer at the wrong rokowaniu and method and diagnostic kits for the development of new bad prognosis marker for prostate cancer.JAN...
We also found a positive correlation between Ki67 and ARHGEF38 in prostate cancer. The higher expression of both worsened the prognosis. Taken together, our results reveal that ARHGEF38 might play a crucial role in tumorigenesis and metastasis of human PCa and might function as a potential ...
Survival analysis indicated that individuals with high expression of ERRα had lower prognosis (P=0.041), and survival curves were shown in Figure 7B. Furthermore, COX multivariate analysis indi- cated that when the prognostic factors (P<0.1) in the univariate analysis were included in the ...
In this study, we have investigated the role of squalene epoxidase (SQLE, also known as squalene monooxygenase)14, a rate-limiting enzyme of cholesterol synthesis and known cancer-related gene in PCa, whose expression is correlated with poor prognosis and survival in this entity15,16. We confir...
The role of dysregulation of mRNA alternative splicing (AS) in the development and progression of solid tumors remains to be defined. Here we describe the first comprehensive AS landscape in the spectrum of human prostate cancer (PCa) evolution. We find
Men with progressive neuroendocrine or aggressive-variant metastatic prostate cancer (NEPC/AVPC) have a poor prognosis and limited treatment options, and immunotherapy has not been tested in such patients. We conducted an open label single center phase 2
Campa D, Kaaks R, Le Marchand L, Haiman CA, Travis RC, Berg CD, Buring JE, Chanock SJ, Diver WR, Dostal L, et al: Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. J National Cancer Inst. 2011, 103 (16): 1252-...