The present invention is also concerned with the use of a particular DPP-4 inhibitor and an anti-hypertensive agent selected from the group consisting of an angiotensin II receptor antagonist and an ACE inhibitor, for the manufacture of a medicament for the treatment of diabetes, diabetes associate...
The reaction mixture, orange in color, was diluted by pouring into a large volume of ice water. The diluted solution was added in small portions to a saturated aqueous sodium hydrogencarbonate solution to precipitate orange needle crystals. The crystals were collected by filtration and dried to ...