The Bioarchaeology of Metabolic Bone Disease (Second Edition)Brickley M. 2002. An investigation of historical and archeological evidence for age-related bone loss and osteoporosis. International Journal of Osteoarchaeol- ogy 12: 364-371.S. Khosla, B.L. Riggs, Pathophysiology of age-related bone ...
von Wowern N, Stoltze K. The pattern of age related bone loss in man- dibles. Scand J Dent Res. 1980;88:134-146.Von Wowern N, Stoltze K. Pattern of age related bone loss in mandibles. Scand J Dent Res. 1980; 88:134-146. [PubMed: 6929561]...
They do not adapt to these diets by increasing the efficiency of calcium absorption as young persons do. This altered regulation of calcium may contribute to the chronic depletion of calcium from bone in later years, a condition known as age-related osteoporosis....
There are few data on osteoporosis in men, but cross-sectional studies have shown that age-related bone loss in men is of lower magnitude than in women. To elucidate some controversies related partially to methodological aspects, we measured bone mineral density (BMD) by dual-energy X-ray abso...
Simulated Interventions to Ameliorate Age-Related Bone Loss Indicate the Importance of Timing 来自 NCBI 喜欢 0 阅读量: 38 作者:CJ Proctor,G Alison 摘要: Bone remodeling is the continuous process of bone resorption by osteoclasts and bone formation by osteoblasts, in order to maintain homeostasis. ...
TGFβ1 induces age-related bone loss by promoting degradation of TNF receptor-associated factor 3 (TRAF3), levels of which decrease in murine and human bone during aging. We report that a subset of neutrophils (TGFβ1+CCR5+) is the major source of TGFβ1 in murine bone. Their numbers ...
A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.
Although data from rodent systems are extremely useful in providing insights into possible mechanisms of age-related bone loss, concepts evolving from animal models need to ultimately be tested in humans.This review provides an update on mechanisms of age-related bone loss in humans based on the ...
Age-related bone loss is an important risk factor for fractures in the elderly; it results from an imbalance in bone remodeling mainly due to decreased bone formation. We have previously demonstrated that endogenous G protein–coupled receptor (GPCR)-driven Gi signaling in osteoblasts (Obs) restrai...
Fig. 1: αKG increases the bone mass of aged female mice. Full size image αKG attenuates age-related bone loss Fig. 2: αKG attenuates age-related bone loss. Full size image αKG accelerates bone defect healing of aged rodents