Definition These cells are set aside during development in order to provide a source for replenishment of tissue over time in response to damage or simply wear and tear. Stem Cell TelomeresDefinitionThese cells are set aside during development in order to provide a source for replenishment of ...
adult stem cells do not normally generate cell types foreign to their native tissue/organ. Adult stem cells reside in specificstem cell nichesand have been found in the bone marrow, the peripheral blood, postnatalumbilical cord, the skin, the cornea and thegastrointestinal tract, amongst others....
One preferred therapeutic concept is the stepwise induction of neovascularization followed by activation of the solid-organ resident stem cell pool. Cardiac tissue repair in patients with acute myocardial infarction is currently at the forefront of clinical stem cell treatment research. The outcome of ...
Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity Long-term maintenance of tissue homeostasis relies on the accurate regulation of somatic stem cell activity. Somatic stem cells have to respond to tissue d... Benoit,Biteau,and,... - 《Cell Stem Cell》 被引量: 233发...
Finally, we detail the potential involvement of the SC niche in tissue degeneration, with a particular emphasis on aging and cancer.doi:10.1016/B978-0-12-416022-4.00012-3Amélie RezzaRachel SennettMichael RendlPubMedCurrent Topics in Developmental Biology...
The naked mole rat (NMR), Heterocephalus glaber, the longest-living rodent, provides a unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity and tissue function with increasing lifespan. Using cumulative BrdU labelling and
Embryonic stem cells are the only type of stem cells that are pluripotent. Embryonic stem cells within the first few cell divisions after forming the zygote are called totipotent. This means that they can become any cell type in the body and any extraembryonic tissue as well. Embryonic Stem ...
ous adipose tissue. Characterization of human adult stem-cell populations isolated from visceral and subcutaneous adipose tissue.Characterization of human adult stem-cell populations isolated from visceral and subcutaneous adipose tissue.doi:10.1096/fj.08-196946...
Adult stem cells maintain tissue homeostasis by their ability to both self-renew and differentiate to distinct cell types. Multiple signaling pathways have been shown to play essential roles as extrinsic cues in maintaining adult stem cell identity and activity. Recent studies also show dynamic regulat...
The spiny mouse, Acomys cahirinus, is an adult mammal capable of remarkable feats of scar-free tissue regeneration after damage to several organs including the skin and the heart. Here we investigate the regenerative properties of the skeletal muscle of