Cells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypes. Am Surg 1999; 65 (1): 22-6.Williams JT, Southerland SS, Souza J, Calcutt AF, Cartledge RG. Cells isolated from adult human skeletal muscle capable of differentiating into multiple ...
Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat. Immunol. 13, 1072–1082 (2012). Article CAS PubMed Google Scholar Adams, G. B. et al. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing ...
Skeletal muscle contains at least two distinct populations of adult stem cells - satellite cells and multipotent muscle-derived stem cells. Monopotential satellite cells are located under the basal lamina of muscle fibers. They are capable of giving rise only to cells of myogenic lineage, which ...
Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal Muscle 2016, Stem Cell Reports Citation Excerpt : Furthermore, interstitial PDGFRα+ mesenchymal progenitors do express EGFR (Figure S4B), indicating that this marker cannot distinguish satellite cells from ...
Satellite cells, the stem cells of skeletal muscle, are responsible for muscle development and regeneration. Although low in abundance, satellite cells can be isolated from muscle but cannot be propagated successfully in culture in numbers needed for therapeutic use. We developed a method to generate...
Muscle satellite cells are a self-renewing pool of stem cells that give rise to daughter myogenic precursor cells in adult skeletal muscle, where they function in postnatal tissue growth and regeneration. Adult skeletal muscle also contains a novel stem cell population purified as a side population...
and peripheral nervous systems and skeletal muscle; it is also possible that all organs and tissues are derived from, and still contain, stem cells. Beca... Weissman,L I. - 《Science》 被引量: 2021发表: 2000年 Transdifferentiation potential of human mesenchymal stem cells derived from bone ma...
Skeletal muscleRegenerationMyogenesisHeterogeneitySkeletal muscle regeneration is a finely tuned process involving the activation of various cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are indispensable for skeletal muscle regeneration. Their functionality is critically ...
However, a more reliable marker of satellite cells in human muscle is CD56 (neural cell adhesion molecule) [30]. The assessment of differentiation potential showed that skeletal muscle satellite cells are strictly monopotential –they are committed to myogenesis [31,32]. 4. Multipotent muscle–...
Adult stem cells can be isolated from different tissues, such as skeletal muscle, adipose tissue, peripheral blood or bone marrow (BM), while ESCs and iPSCs are pluripotent stem cells that are isolated from blastocysts of human embryos and derived via reprogramming from somatic cells, respectively...