The mediated signaling pathway, in regulating the cellular function of proteins, regulates the cell attachment, and migration on the scaffold biomaterial [103]. Absorbed protein regulates the cellular functions via integrin mediation signaling pathways that control cell proliferation and cell arrangements [...
Many biological processes on the molecular level are associated with membrane-bound receptors or other integral membrane proteins. We have been working with proteins that are domains of receptors, or inhibit their function. The first topic are the T-cell surface glycoprotein receptor CD2 and its ...
摘要: The discovery that the tumour-suppressor NF2, also known as merlin /schwannomin, is related to ERM proteins has added a new impetus to investigations of their roles. ... Author Keywords: ERM protein; ezrin; radixin; moesin; cytoskeleton; merlin ; neurofibromatosis; cell adhesion. ......
The functional units of cell adhesion are typically multiprotein complexes made up of three general classes of proteins; the adhesion receptors, the cell-e... Jianguo,Gu,Tomoya,... - 《Glycoconjugate Journal》 被引量: 94发表: 2012年 Membrane protein glycosylation and CD44 content in the adhesio...
Multifunctional ECM proteins in bone and teeth. Exp. Cell. Res. 325, 148–154 (2014). Article CAS PubMed PubMed Central Google Scholar Ekdahl, K. N. et al. Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thrombo...
Similarly, immunohistochemistry (IHC) and western blot analysis of myelin basic protein (MBP) and proteolipid protein (PLP), two markers for mature OLs and CNS myelin, showed significant reductions of the two proteins in Gpr56−/− mice compared with controls (Fig. 1c–e and Supplementary ...
Coexpression of dominant-negative mutants of Rab4 and Rab11, two proteins involved in endosomal recycling, also inhibited the migration (Figures 4H and S3, Video S6). Altogether these results show that RhoA activity at the cell rear polarizes intracellular membrane trafficking and this is ...
Malignant cancer transformation is closely associated with the down-regulation of adhesion proteins and the consequent reduction of adhesion forces. By analyzing the size and distribution of adhesion patches from a benign and a malignant human pancreatic tumor cell line, we established a model for ...
Integrinsare everywhere in our bodies! They are very special because they are transmembrane receptors, like a "phone", on the cell membrane that help conveying messages both inside-out and outside-in. Integrins work with a lot of other intracellular and extracellular membrane proteins to mediate ...
Finally, we present evidence that adhesion to the UF membrane surface is mediated by cell-surface macromolecules (likely to be outer membrane proteins and pili) which, upon contacting the membrane, undergo surface-induced unfolding. 展开 DOI: 10.1021/acs.est.7b03682 年份: 2017 ...