摘要: The discovery that the tumour-suppressor NF2, also known as merlin /schwannomin, is related to ERM proteins has added a new impetus to investigations of their roles. ... Author Keywords: ERM protein; ezrin; radixin; moesin; cytoskeleton; merlin ; neurofibromatosis; cell adhesion. ......
ERM proteins in cell adhesion and membrane dynamics. Trends Cell Biol 9: 187-192, 1999.Mangeat P, Roy C, Martin M: ERM proteins in cell adhesion and membrane dynamics. Trends Cell Biol 1999, 9:187-192.Mangeat, P., Roy, C., and Martin, M. (1999). ERM proteins in cell...
Malignant cancer transformation is closely associated with the down-regulation of adhesion proteins and the consequent reduction of adhesion forces. By analyzing the size and distribution of adhesion patches from a benign and a malignant human pancreatic tumor cell line, we established a model for ...
Scarless fetal wounds have an enhanced ability to upregulate ECMadhesion proteins, such as tenascin and fibronectin (Whitby and Ferguson, 1992, Casset al., 1995, Whitbyet al., 1991). These adhesion proteins mediate cellular attachment to the ECM and attract fibroblasts, keritinocytes, and endothe...
Multifunctional ECM proteins in bone and teeth. Exp. Cell. Res. 325, 148–154 (2014). Article CAS PubMed PubMed Central Google Scholar Ekdahl, K. N. et al. Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thrombo...
Cell adhesion is the binding of a cell to a surface, extracellular matrix (ECM), or another cell using cell adhesion molecules, which are integral membrane proteins that have cytoplasmic, transmembrane, and extracellular domains. The extracellular domains of adhesion molecules extend from the cell an...
Integrinsare everywhere in our bodies! They are very special because they are transmembrane receptors, like a "phone", on the cell membrane that help conveying messages both inside-out and outside-in. Integrins work with a lot of other intracellular and extracellular membrane proteins to mediate ...
The formation of cell adhesion involves not only the recognition and binding of structural proteins but also the generation and transmission of mechanical forces during this process [1]. In nature, multicellular organisms require a 3-dimensional superstructure not only to provide structural integrity to...
The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells. Hum. Mol. Genet. 26, 624–636 (2017). Article CAS PubMed Google Scholar Scholz, N. Cancer cell mechanics: adhesion G protein-coupled receptors in action? Front. Oncol. 8...
The methyl group modified on α-CD promotes the adsorption of serum-derived cellular adhesion proteins [32,33], which may contribute to the promotion of cellular adhesion of PRX/collagen hydrogels. These results suggest that the PRX/collagen hydrogel is a promising implantable scaffold, with ...