The involvement of β-oxidation in this biosynthetic pathway is supported by an observation that only an even number of carboxylic acid side chains of OPC derivatives were used for JA synthesis [65]. Plant peroxisomal β-oxidation involves the sequential action of enzymes from three gene families;...
A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic a... Arabidopsis thaliana contains a large number of genes that encode carboxylic acid-activating enzymes, including nine long-chain fatty acyl-CoA ...
To study the ability of the tested enzyme to remodel PC molecules containing fatty acids from the VLC-PUFA biosynthetic pathway the tested microsomes were enriched biochemically with: sn -1-18:1- sn -2-18:3(n-3)-PC, sn -1-18:1- sn -2-18:3(n-6)-PC, sn -1-18:1- sn -2-18...
Figure 2.Biosynthetic pathways of plasmalogens. The figure was slightly modified and originally published inRef. [5]. The pathophysiologic roles of Pls are poorly understood. Some patients withperoxisomal disordersexhibit systemic reduction of Pls and various pathologic conditions including severe mental re...
of WE biosynthetic pathway in heterologous host, but further much more work is needed in order to investigate the potential of utilizing theseT. roseumWS/DGATs to produce high levels of novel WEs through metabolic engineering approach. Methods ...
Eukaryotes can utilize not only endogenous LCBs produced via de novo biosynthetic pathways but also exog- enous LCBs for sphingolipid synthesis. For example, food contains abundant sphingolipids: per capita sphingo- lipid consumption is estimated to be 300–400 mg per day17. Dietary sphingolipid...
Recuero-Checa1,2,*, Manu Sharma1,*, Constance Lau1, Paul A. Watkins3,4, Charlotte A. Gaydos2 & Deborah Dean1,5 The obligate-intracellular pathogen Chlamydia trachomatis (Ct) has undergone considerable genome reduction with consequent dependence on host biosynthetic pathways,...
Oil in the form of triacylglycerols (TAGs) is quantitatively the most important storage form of energy for eukaryotic cells. Diacylglycerol acyltransferase (DGAT) is considered the rate-limiting enzyme for TAG accumulation. Chlorella, a unicellular eukar
The biosynthetic routes for many lepidopteran pheromone components have been found to involve unique desaturases, such as the Δ11-desaturase found only in the pheromone glands of female moths (Roelofs and Wolf, 1988). The cabbage looper moth, uses a Δ11-desaturase that acts on saturated 16-...
Applying CATNIP to profile the susceptibility of acetyltransferases led to the characterization of two RNA modifications sensitive to disruption of the acetyl-CoA biosynthetic enzyme ACLY. Finally, we demonstrated an unbiased workflow for analysis of CATNIP binding data that can be used to detect ...