Leukemia, Promyelocytic, AcuteAntineoplastic AgentsPrognosisTretinoinThe most impressive clinical feature of acute promyelocytic leukemia (APL) at diagnosis is the presence in 80% to 90% of patients of a severe hemorrhagic syndrome. Recent data favor a fibrinolytic/proteolytic process rather than a ...
联合三氧化二砷序贯治疗急性早幼粒细胞白血病临床观察 www.ilib.cn 10. Therelationshipofadditionalchromosomeabnormalitieswithprognosisinacutepromyelocyticleukemia 急性早幼粒细胞白血病附加染色体异常与预后的关系 www.ilib.cn 1 2 3 4 5
From molecular interaction to acute promyelocytic leukemia: Calculating leukemogenesis and remission from endogenous molecular-cellular network Ruoshi Yuan Xiaomei Zhu Ping Ao Scientific Reports (2016) Significance of oncogenes and tumor suppressor genes in AML prognosis Maria Kavianpour Ahmad Ahmadzadeh...
It is concluded that acute promyelocytic leukemia is a unique disease with a high potential for cure. Knowledge of its prognosis using present frontline and salvage therapy, of the factors related to fatal hemorrhage, and of the unusual patient marrow profiles during remission induction may improve ...
13.Study of the action of glutathione Mdr1,S-transferase expressionin acute promyelocytic leukemia cell急性早幼粒细胞白血病mdr1、GSTπ表达与耐药的关系 14.Analysis of Prognosis Factors in 54 Patients with Acute Promyelocytic Leukemia急性早幼粒细胞白血病54例预后因素分析 15.Analysis of Factors on Long-...
Earlier in treatment, slightly higher PCR ratios seem to be allowable for a favorable prognosis; as treatment continues, lower cutoff values of PCR ratios associated with favorable outcomes are required. At the higher end of this cutoff, for example, one study found favorable continuous CR rates ...
It is concluded that acute promyelocytic leukemia is a unique disease with a high potential for cure. Knowledge of its prognosis using present frontline and salvage therapy, of the factors related to fatal hemorrhage, and of the unusual patient marrow profiles during remission induction may improve ...
I think of acute promyelocytic leukemia—used to be one of the worst prognostic leukemias. Now we’re not using traditional chemotherapy, and it’s got a very good prognosis. One thing we haven’t talked about a lot today is T-cell ALL, which I feel some sadness about in all the ...
Table 2 Cytogenetic-molecular entities in acute myeloid leukemia (NCCN classification). Full size table Molecular subsets also define prognosis and are therapeutically targetable. Among patients with a diploid karyotype, single mutations and mutation combinations interact differently, in sometimes intricate ba...
Purpose: The current stratification system for acute promyelocytic leukemia (APL) is based on the white blood cell (WBC) and the platelet counts (i.e., Sanz score) over the past two decades. However, the borderlines among different risk groups are sometimes ambiguous, and for some patients,...