Acute promyelocytic leukemia; Early diagnosis is the key to survival[J].The American journal of emergency medicine 2013,8(8).Roldan CJ, Haq SM, Miller AH. Acute promyelocytic leukemia; early diagnosis is the key to survival. Am J Emerg Med 2013; 31:1290e1-2....
Historically, acute promyelocytic leukemia (APL) was considered to be one of the most fatal forms of acute leukemia with poor outcomes before the introduction of the vitamin A derivative all-transretinoic acid (ATRA). With considerable advances in therapy, including the introduction of ATRA initially...
医生分析：急性早幼粒细胞白血病属于急性髓系白血病中的一种，也就是M3,多数病人伴有PML/RARa融合基因阳性表达，治愈率很高，亚砷酸、维甲酸、中药雄黄都是这个病的特效药物。现在病人有肺部感染，化疗后机体免疫功能下降，加重感染，不容易控制。医生建议：先抗感染治疗后再考虑化疗，如果抗生素治疗效果不...
These cases are difficult (or impossible) to diagnose morphologically (under the microscope) – you really need special tests like immunophenotyping in order to make a definitive diagnosis. Other cases of acute leukemia have obvious morphologic clues. Acute promyelocytic leukemia (APL) falls into the...
Acute myeloid leukemia is one of the most common types of leukemia among adults according to data from the Leukemia and Lymphoma Society(R). tipschina.gov.cn 根据白血病和淋巴瘤协会的数据, 急性 髓细 胞白血病是成人中最常见的白血病类型之一。 tipschina.gov.cn [...] squamous cell carcinoma...
ObjectiveToexplorenursingofacutepromyelocyticleukemia(APL)combinedwith DIC. 目的探讨急性早幼粒细胞白血病(APL)合并DIC的护理体会。 journal.9med.net 4. Inductiondifferentiationtherapyof usingAll-transretinoic acidhas alreadybeen thefirstlinetherapyforacutepromyelocyticleukemia. ...
The latter finding consists of azurophilic, often needle-shaped cytoplasmic inclusion bodies that are commonly seen in APL, acute myelomonocytic leukemia and the majority of AML with t(8;21). The diagnosis of AML can also be established in the presence of an extramedullary tissue infiltrate, or ...
According to both guidelines, the finding of a translocation between chromosomes 15 and 17, or t(15;17), is associated with a diagnosis of acute promyelocytic leukemia (APL), an AML subtype that is treated and monitored differently than other subtypes. [28, 119] Treatment Both the NCCN and...
Acute promyelocytic leukemia(APL) is characterized by the t(15;17) chromosomal translocation leading to the formation of the PML-RARalpha oncoprotein. This... D Grimwade,AR Mistry,E Solomon,... - 《Cancer Treat Res》 被引量: 750发表: 2010年 Management of acute promyelocytic leukemia Extramedul...
Molecular analysis for the promyelocytic leukemia-retinoic acid receptor α (PML-RARα) hybrid gene at diagnosis was performed in 16 patients by means of reverse transcription-polymerase chain reaction (RT-PCR) analysis, and all were RT-PCR+ for the hybrid gene. In the remaining 4 patients, ...