Hope KJ,Jin L.Dick JE: Human acute myeloid leukemia stem cells. Archives of Medical Research . 2003Hope, K. J., Jin, L. and Dick, J. E. (2003) 'Human acute myeloid leukemia stem cells', Arch Med Res 34(6): 507-14.Hope KJ, Jin L, Dick JE. Human acute myeloid leukemia stem...
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy primarily driven by an immature population of AML cells termed leukemia stem cells (LSCs) that are implicated in AML development, chemoresistance, and relapse. An emerging area of research in AML focuses on identifying and targetin...
Cite this: Acute Myeloid Leukemia Stem Cells: Seek and Destroy - Medscape - Dec 01, 2009. Abstract and Introduction Models of Leukemogenesis LSC Biology & Unique Therapeutic Targets Expert Commentary Five-year View References SidebarRecommendations Revumenib Approved for R/R Acute Leukemia With KMT...
Acute myeloid leukemia (AML) is a clonal disorder defined by the accumulation of abnormally differentiated myeloid cells that are not mature; any myeloid lineage can be affected and the extent of maturation of the leukemia blasts can also vary. Because mature blast cells of AML have very limited...
Zhou HS,Carter BZ,Andreeff M.Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia:Yin and Yang[J].Cancer Biol Med,2016,13(2):248-259.Zhou, H.S.; Carter, B.Z.; Andreeff, M. Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid ...
Allogeneic stem cell transplantation in acute myeloid leukemia Deutsches rzteblatt InternationalZander ARBacher UFinke J
Stressing the stem cell in acute myeloid leukemia doi:10.3324/haematol.2023.283919HaematologicaGautam Borthakur
Acute myeloid leukemia (AML) is a hematologic malignancy due to aberrant differentiation and proliferation of hematopoietic stem cells with myeloid blast buildup in the blood, marrow, and other body organs [1]. The average age of diagnosis is about 68 years and is more common in the elderly ...
Therapy for acute myeloid leukemia (AML) involves intense cytotoxic treatment and yet approximately 70% of AML are refractory to initial therapy or eventually relapse. This is at least partially driven by the chemo-resistant nature of the leukemic stem cells (LSCs) that sustain the disease, and ...
Acute myeloid leukemia stem cells (AMLSC) are identified. The cells can be prospectively isolated or identified from patient samples, and are shown to possess the unique properties of cancer stem cells in functional assays for cancer stem cell self-renewal and differentiation, and in cancer diagnos...