This study was designed to correlate the clonogenic capacity of acute myeloid leukemia (AML) cells with P-glycoprotein (P-gp) expression level and P-gp-mediated efflux capacity. Fifty AML cell samples were tested for P-gp expression using MRK16 monoclonal antibody and flow cytometry. Among them...
Cancer vaccines are promising treatments to prevent relapse after chemotherapy in acute myeloid leukemia (AML) patients, particularly for those who cannot tolerate intensive consolidation therapies. Here, we report the development of an AML cell membrane-coated nanoparticle (AMCNP) vaccine platform, in ...
Hope KJ,Jin L.Dick JE: Human acute myeloid leukemia stem cells. Archives of Medical Research . 2003Hope KJ, Jin L, Dick JE. Human acute myeloid leukemia stem cells. Arch Med Res 2003;34:507-14.Hope KJ, Jin L, Dick JE. Human acute myeloid leukemia stem cells. Arch Med Res 2003;34...
和CAR-T细胞不同,NK细胞生命周期短,体内扩增受限,因而提高了其安全性,即使是异体细胞过继治疗,也相对安全,几乎不发生CRS和神经毒性,使得NK细胞可以做成off-the-shelf的产品,增加细胞治疗可及性。
Acute myeloid leukemia( AML ) is a clonal and heterogeneous disease characterized by a myriad of genetic defects. 急性髓性白血病 ( acutemyeloid leukemia, AML ) 是一类起源于造血干细胞的、以大量遗传缺陷为特征的异质性恶性血液病. 互联网 Methods: Induction regiment ofacute myeloid leukemia( AML ) co...
ato ___ with the local police.[translate] ahemostasis hemostasis[translate] athe tenth anniversary 第十周年纪念[translate] aThe left over food from guest must be discarded. 必须放弃左边结束食物从客人。[translate] aAcute myeloid leukemia 急性骨髓状白血病[translate]...
Acute myeloid leukemia (AML) is a type of blood cancer. It starts in your bone marrow, the soft inner parts of bones. AML usually begins in cells that turn into white blood cells, but it can start in other blood-forming cells, as well. ...
A hierarchy of progenitor cells is thought to exist in human acute myeloid leukemia (AML), with only the most primitive cells capable of proliferating to maintain the malignant clone. To further characterize this AML cell hierarchy, we evaluated the coexpression of CD34 and c-kit (CD117) on ...
The stem cells of acute myeloid leukemia (AML) are the malignancy initiating cells whose survival ultimately drives growth of these lethal diseases. Here we review leukemia stem cell (LSC) biology, particularly as it relates to the very heterogeneous nature of AML and to its high diseas...
Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. In AML, the bone marrow makes abnormal red blood cells, platelets, or myeloblasts (a type of immature white blood cell). These abnormal cells are called “blasts” and are the leukemia cells. These cells ...