E. (2003) 'Human acute myeloid leukemia stem cells', Arch Med Res 34(6): 507-14.Human acute myeloid leukemia stem cells. Hope KJ,Jin L,Dick JE, et al. Archives of Medical Research . 2003K. J. Hope, L. Jin, J. E. Dick. Human acute myeloid leukemia stem cells. Archives of ...
急性髓系白血病(Acute myeloid leukemia, AML)是最常见的白血病类型之一,且难以治愈。AML的特征在于快速增长的异常细胞,积聚在骨髓和血液中,进而干扰正常血细胞。其症状包括感到疲倦,呼吸急促,容易瘀伤和出血以及感染风险增加。AML的进展较为迅速,如果不及时治疗,通常会有生命危险。 临床研究,指任何在人体(病人或健康志...
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy primarily driven by an immature population of AML cells termed leukemia stem cells (LSCs) that are implicated in AML development, chemoresistance, and relapse. An emerging area of research in AML focuses on identifying and targetin...
Acute myeloid leukemia( AML ) is a clonal and heterogeneous disease characterized by a myriad of genetic defects. 急性髓性白血病 ( acutemyeloid leukemia, AML ) 是一类起源于造血干细胞的、以大量遗传缺陷为特征的异质性恶性血液病. 互联网 Methods: Induction regiment ofacute myeloid leukemia( AML ) co...
Acute myeloid leukemia (AML) is a type of blood cancer that starts in your bone marrow, which is the soft inner part of your bones where all your blood cells are made. AML usually begins in cells that turn into white blood cells but can also start in other blood-forming cells. When ...
Cancer vaccines are promising treatments to prevent relapse after chemotherapy in acute myeloid leukemia (AML) patients, particularly for those who cannot tolerate intensive consolidation therapies. Here, we report the development of an AML cell membrane
The stem cells of acute myeloid leukemia (AML) are the malignancy initiating cells whose survival ultimately drives growth of these lethal diseases. Here we review leukemia stem cell (LSC) biology, particularly as it relates to the very heterogeneous nature of AML and to its high disease relapse...
Acute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion and differentiation arrest of the myeloid progenitor cells, which leads to the accumulation of immature cells called blasts in the bone marrow and peripheral blood. ...
Acute Myeloid Leukemia AcuteMyeloidLeukemia BySiTing WhatisAML?Acutemyeloidleukemia(AML)•isamalignanthematologicaldisorder•thebonemarrowmakesabnormalmyeloblasts—precursoroferythrocyte,plateletandgranulocyte•clonalproliferationofmyeloidprecursorcellswithreducedcapacitytodifferentiateintomorematurecells.Normally,thebone...
Natural killer cell therapy for acute myeloid leukemia. In patients with AML, downregulation of HLA-1 expression in AML cells and a decrease in the expression of activating receptors, such as NCR and DNAM-1, have been observed. In addition, NK cell function is suppressed by inhibitory receptor...