Background:Achievement of initial remission remains the most important clinical factor predicting long term survival in acute myeloid leukemia (AML) patients treated with intensive chemotherapy. Yet, whether the patient subset in need of a second cycle of intensive induction chemotherapy to reach ...
An aggressive chemotherapy regimen, i.e.an anthracyclin plus cytarabine (ARA-C), was given to 22 patients (35%); 7 patients (11%) received low-dose ARA-C (LD-ARA-C) and, finally, 33 (53%) were managed with supportive care only and/or hydroxyurea (HU) in case of leukocytosis ...
There are few molecular biologic determinants that are prognostic for patients with acute myeloid leukemia (AML). Hence, we examined whether cellular levels of the cyclin-dependent kinase inhibitor p27in acute myeloid leukemia could be used to predict clinical outcome in AML. Using immunoblot ...
acute myeloid leukemia (AML)central nervous system (CNS)prophylactic cranial irradiationSummary To evaluate whether a lower dose of prophylactic cranial irradiation in children with acute myeloid leukemia (AML) is sufficient to prevent central nervous system (CNS) relapse of leukemia. Patients with Down...
mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction—a retrospective propensity score analysisClonal hematopoiesis of indeterminate potential (CHIP) is linked to leukemia gene mutations and associates with an increased risk for coronary artery disease and...
Patients with acute myeloid leukemia (AML) present with signs and symptoms resulting from bone marrow failure, organ infiltration with leukemic cells, or both. The time course is variable. Some patients, particularly younger ones, present with acute symptoms that develop over a few days to 1-2 ...
3.1 Acute myeloid leukemia Acute myeloid leukemia (AML) is a heterogeneous aggressive hematological malignancy that is characterized by the clonal expansion and differentiation arrest of myeloid hematopoietic progenitor cells in the bone marrow [41]. AML patients are diagnosed according to the categories ...
[医]急性髓细胞样白血病;例句:1.The drug also blocked the growth of acute myeloid leukemia ( aml) stem cells taken frompatients.甲硫达嗪还能阻止采于患者的急性髓细胞性白血病（aml）干细胞的生长。2.Mortality in overweight and underweight children with acute myeloid leukemia.急性髓系白血病...
OBJECTIVE: To evaluate in a multicenter retrospective study, the clinical and laboratory characteristics and the outcome of patients with acute myeloid leukemia (sAML) previously diagnosed with breast cancer (BC) among an adult acute leukemia population. PATIENTS AND METHODS: Between June 1992 and July...
Mutant Isocitrate dehydrogenase (mIDH) inhibitors, enasidenib or Ivosidenib, in combination with azacitidine (AZA): preliminary results of a phase 1b/2 study in patients with newly diagnosed acute myeloid leukemia (AML). Blood. 2017;130(Suppl 1):639. Google Scholar Stein EM, DiNardo CD, ...