Autologous stem cell transplantation for acute myeloid leukemia in first remission. Biol Blood Marrow Transplant 2000; 6: 50-57.Linker CA. Autologous stem cell transplantation for acute myeloid leukemia. Bone Marrow Transplant. 2003 May;31(9):731-8....
Leukemia, Myeloid, AcuteMaleThe 10th United Kingdom Medical Research Council (MRC) AML trial showed a reduced overall relapse rate compared to previous trials, attributed largely to increased treatment intensity. Autologous...doi:10.1007/978-3-642-71960-8_126Goldstone, A. H....
Progress in the understanding of the biology and therapy of acute myeloid leukemia (AML) is occurring rapidly. Since 2017, nine agents have been approved for various indications in AML. These included several targeted therapies like venetoclax, FLT3 inhi
June 10 -- TUESDAY, June 9 (HealthDay News) -- For most patients with acute myeloid leukemia (AML) who come out of remission, donor stem cells appear to offer the best shot at survival, a new analysis shows. AML is the most common form of acute leukemia, striking about 12,000 ...
Park, Chan-JeoungSeo, Jong JinPediatric TransplantationSuh JK, Lee SW, Koh KN, et al. Hematopoietic stem cell transplantation in pediatric patients with acute myeloid leukemia without favorable cytogenetics. Pediatr Transplant 2017;21:e13004.
Little is known about how leukemia cells alter the bone marrow (BM) niche to facilitate their own growth and evade chemotherapy. Here, we provide evidence that acute myeloid leukemia (AML) blasts remodel the BM niche into a leukemia growth-permissive and
Acute myeloid leukemia (AML) is a hematologic malignancy due to aberrant differentiation and proliferation of hematopoietic stem cells with myeloid blast buildup in the blood, marrow, and other body organs[1]. The average age of diagnosis is about 68 years and is more common in the elderly pop...
Stem Cell Transplants:are in their infancy in the UK as a treatment option. The stem cells may come from a family member (an allogeneic transplant) or may be your own (an autologous transplant) which were collected and frozen until you need them. In the USA, newly diagnosed patients under...
allogeneic stem cell transplantation; acute myeloid leukemia; refractory disease; graft-versus-host disease; reduced-intensity conditioning Abstract For patients with refractory acute myeloid leukemia (AML), allogeneic stem cell transplantation (alloSCT) represents the only curative approach. We here analyzed...
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an incidence of over 20 000 cases per year in the United States alone. Large chromosomal translocations as well as mutations in the genes involved in hematopoietic prolifer