Mixed phenotype acute leukemiaMinimal residual diseaseFlow cytometry plays an indispensible role in the diagnosis and subclassification of acute myeloid leukemia (AML). Using a multiparametric approach, flow cytometry immunophenotyping has the advantage of efficiency with high sensitivity. This article reviews...
Acute Myeloid Leukemia Diane C. Farhi GENERAL FEATURES Nomenclature Acute leukemia arising from myeloid cells has been variously referred to as myeloblastic, myelocytic, and myeloid, with little, if any, clarification as to the meaning implied by these different terms. In this chapter, the overall ...
acute myeloid leukemia (AML); blasts; leukemia stem cells (LSCs); measurable/minimal residual disease (MRD); immunophenotype; multiparametric flow cytometry (MFC); relapse1. Introduction Acute myeloid leukemia (AML) is a type of blood cancer, characterized by clonal expansion and accumulation of ...
Acute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion and differentiation arrest of the myeloid progenitor cells, which leads to the accumulation of immature cells called blasts in the bone marrow and peripheral blood. ...
LETTERS Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1 Frank Rosenbauer1, Katharina Wagner1, Jeffery L Kutok2, Hiromi Iwasaki3, Michelle M Le Beau4, Yutaka Okuno1, Koichi Akashi3, Steven Fiering5 and Daniel G Tenen1 Transcription factors ...
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an incidence of over 20 000 cases per year in the United States alone. Large chromosomal translocations as well as mutations in the genes involved in hematopoietic prolifer
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up. J. Vis. Exp. (133), e56976, doi:10.3791/56976 (2018). Download Citation Reprints and Permissions JoVE Privacy ...
flow cytometry in the diagnosis and classification of acute myeloid leukemia and detection of minimal residual lesions, raising our concern about the deficiency from the perspective of immunophenotyping markers due to their high degree of cross reactivity and low specificity among M0-M7 types, and ...
- 《Disease Markers》 被引量: 6发表: 2000年 Automated Assessment of Disease Progression in Acute Myeloid Leukemia by Probabilistic Analysis of Flow Cytometry Data Objective: Flow cytometry (FC) is a widely acknowledged technology in diagnosis of acute myeloid leukemia (AML) and has been ...
Acute myeloid leukemia (AML) is a heterogeneous, and if not treated, fatal disease. It is the most common cause of leukemia-associated mortality in adults. Initially, AML is a disease of hematopoietic stem cells (HSC) characterized by arrest of differentiation, subsequent accumulation of leukemia...