信号转导和转录激活因子3(Signal transducer and activator of transcription 3, STAT3)是转录因子家族中的一员,广泛存在于各类细胞和组织中,在调节细胞增殖、存活、凋亡、分化及转移等方面有重要作用。 STAT3的激活与705位酪氨酸(Tyr705)和727位丝氨酸(Ser727)的磷酸化密切相关。其中,STAT3 Tyr705磷酸化介导STAT3经典...
Our research has previously identified that higher levels of signal transducer and activator of transcription 3 ( STAT3 ) within cells correlate with resistance to EBV lytic reactivation. We now investigate whether inhibiting function of STAT3 promotes susceptibility of latently infected B cells to known...
针对STAT3 (Signal transducer and activator of transcription 3) BioAssay ELISA Kit (Human)该产品的特点优势,欢迎查阅官网提供的产品说明书。保存建议 建议收到STAT3 (Signal transducer and activator of transcription 3) BioAssay ELISA Kit (Human)产品后将其置于4°C至-20°C保存。其他...
结果表明:KT-333在外周血单核细胞中实现了高达88%的平均最大STAT3降解,有STAT3通路抑制(SOCS3减少)和外周血中炎症生物标志物下调的证据;最常见的治疗引起的不良事件为1-2级疲劳、贫血和胃肠道症状,没有DLT或药物相关的SAE;Ia期剂量递增正在进行中,并继续入组至剂量水平4(0.4 mpk)。 Kymera对STAT3 PROTAC化合物...
英文名称:Signal Transducer And Activator of Transcription 3 (STAT3) Antibody,中文名称:信号转导与转录激活因子3(STAT3)抗体,产品货号:Catalogue No: abx125397,STAT3抗体是一种抗STAT3的兔单克隆抗体。靶点STAT3反应性人、小鼠、大鼠宿主
The transcription factor STAT3 (signal transducer and activator of transcription 3) mediates the effects of growth factors and cytokines by regulating gene expression. In many human cancers, including breast and prostate, STAT3 is consti... Franck Madoux,M Koenig,H Sessions,... 被引量: 30发表:...
英文名称:Signal Transducer And Activator of Transcription 3 (STAT3) Antibody,中文名称:信号转导与转录激活因子3(STAT3)抗体,产品货号:Catalogue No: abx132219,【信号转导和转录激活因子3(STAT3)抗体是一种针对信号转导和转录激活因子3(STAT3)的
Accordingly, VZV inhibits the activation of the cellular transcription factors IFN regulatory factor 3 (IRF3) and signal transducers and activators of transcription 1 (STAT1), thereby downregulating antiviral factors, including IFNs. Conversely, in this study, we found that VZV triggers STAT3 ...
STAT3 transcription factorcardiovascular diseaseshemostasisinflammationInvolvement of signal transducer and activator of transcription 3 (STAT3) in inflammation is well known. Recently, a role for STAT3 in platelet activation and platelet production has been suggested. Platelets exhibit important immune ...
产品名称: Rat Signal Transducer and Activator of Transcription 3 (STAT3) ELISA Kit 产品型号: abx256148产品展商: 其它品牌产品文档: 无相关文档 简单介绍 Rat Signal Transducer and Activator of Transcription 3 (STAT3) ELISA KitRat Signal Transducer and Activator of Transcription 3 (STAT3) ELISA Kit ...