A polypeptide designated H400 and its encoding nucleic acid are provided as markers specific for activated human T cells. Activated T cells are detected immunochemically by monoclonal antibodies specific for H400 or for its immunogenic peptide fragments. Activated T cells are also detected by nucleic ...
In contrast, antibodies specific for activation markers, including CD40L-specific antibody, may offer the advantage of selective elimination of activated T cells. Other markers present on activated T cells, such as CD25 (IL-2R), may also provide a means to target specific T-cell populations. ...
Alix and Tsg101, exosome markers. GAPDH and Calnexin, cell plasma markers. E Immunoblot of cellular and exosomal PD-1 and exosome markers (Alix, Tsg101, and CD9) with increasing anti-CD3/CD28 T cell activator concentration in PBMC-T cells in 72 h. F TEM images of PD-1 distribution ...
Markers of activated T lymphocytes and T cell receptor γ/δ+ in patients with multiple sclerosis. Eur Neurol 33:152 Perrella O, Carrieri PB, De MR, Buscaino GA (1993) Markers of activated T lymphocytes and T cell receptor γ/δ + in patients with multiple sclerosis. Eur Neurol 33:152....
(TEC). In the presence of activated T cells, especially CD4+T cells, T cell development was found to be inhibited in thymic organ cultures with markedly reduced cellularity. Thymic transplantation demonstrated that the inhibitory effect was most likely due to a defective microenvironment. As the ...
cell differentiationis induced more coercively, resulting in the expression of many differentiation markers, including TGase1 (Henningset al, 1989;Dlugosz and Yuspa, 1994;Gibsonet al, 1996). We employed these cultured cells to investigate the relationship between cell differentiation and the cleavage...
The results revealed that the number of CD3+ CD4+ T-cellssignificantly decreased whereas the level of blood Treg cells and expression of activation markers CD38 and HLA-DR on CD4+ T-cells significantly increased in TB group compared with the controlgroup (p<0.05). The frequency of Treg cells...
A large proportion of cells with multiple markers were activated, as shown by the expression of Tac and HLA-DR antigens. In 2 patients activated T8+ cells expressing also M1 and Leu 7 markers infiltrated the tumor site. The presence of these activated cells both in involved nodes and tumor...
IN-2 accumulated outside the cells and near the cell surface (Fig.1g, right panel, asterisks). To get more insight into the intracellular trafficking of HIV-1 IN, we induced the expression of either Rab5- or Rab7-red fluorescent protein (RFP), as markers of early and late endosomes, re...
12. A composition according to claim 2 wherein said cord blood T cells and other mononuclear cell components in cord blood do not react to allo-antigens in adult peripheral blood on other cord bloods.Description: STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH This work was partially funded by ...