A polypeptide designated H400 and its encoding nucleic acid are provided as markers specific for activated human T cells. Activated T cells are detected immunochemically by monoclonal antibodies specific for H400 or for its immunogenic peptide fragments. Activated T cells are also detected by nucleic ...
Purpose:Although peripheral T-cell lymphoma, unspecified (PTCL/U), is the most common T-cell tumor in Western countries, no study to date has been based on the application of a wide panel of markers to a large series of patients and asse... P Went,C Agostinelli,A Gallamini,... - 《...
(TME), indicated by increased expression of activation marker CD25 on both helper and cytotoxic T cells (Fig.3c). T cells were not activated in peripheral blood where human HER2 is not expressed, consistent with the requirement for HER2 and CD3 dual engagement to activate T cells and redirect...
For example, memory stem cells (TSCM) and memory cells with naive phenotypes (TMNP) have been detected in T cell populations previously characterized as being naive10,11. B(CoDth45TRSCAMþaCnDd4T5RMONPÀcCeCllsR, 7wþhCicDh6e2xLpþre)s,s naive T cell markers respond rapidly to ...
T cell function and activated CD8+38+45RO+ T cells as progression markers in hemophiliacs with long term HIV infection Z Poulopoulou,C Psarra,V Kapsimali,... 被引量: 0发表: 1997年 Natural history of human immunodeficiency virus infections in hemophiliacs: effects of T-cell subsets, platel...
Under homeostatic conditions, quiescent pancreatic stellate cells (qPSCs) localize in basolateral aspects of acinar cells, or surround perivascular and periductal regions. qPSCs are capable of expressing several protein markers, such as glial fibrillary acidic protein (GFAP), synemin, and desmin, most...
Expression of PD-1, Tim-3, Lag-3 and CD38 on CD8 T cells from the closest pre-therapy time-point to seroconversion was measured by flow cytometry, and correlated with surrogate markers of HIV-1 disease (HIV-1 plasma viral load (pVL) and CD4 T cell count) and the trial endpoint (...
Book2014,Identification of Neural Markers Accompanying Memory ClaudiaGonzález-Espinosa,FabiolaGuzmán-Mejía Explore book Mitogen-Activated Protein Kinases After the production of second messengers and activation of initial kinases (such asPKA,PKC, and CAMKIV),signaling pathwayslead to the activation of an...
Activated T cells have been shown to be able to recirculate into the thymus from the periphery. The present study was aimed to elucidate the functional consequences of thymic homing of activated T cells upon developing thymocytes and thymic epithelial ce
Improved prognosis, reflected by a considerable decrease in the cancer markers, accompanied by an improved quality of life in the patients were observed. In conclusion, potential strategies are currently under development for the large-scale production of effectors cells; therefore, autologous immune ...