Most cell surface markers for CD4 +CD25 + regulatory T cells (Tregs) are also expressed by activated non-regulatory T cells. Recently, CD127 down-regulation was found to identify functional Tregs in healthy individuals, but there are no data from patients with inflammatory conditions. We examined...
T-cell activation by HER2-XPAT protein and its proteolytically activated unmasked HER2-TCE was characterized utilizing primary huPBMCs co-cultured with SKOV3 tumor cells (HER2-high). Incubation with unmasked HER2-TCE for 72 h led to dose-dependent upregulation of the activation marker CD69 on...
The present invention comprises a method for the quantitative or qualitative detection of antigen-specific CD4+ T cells and/ or CD8+ T cells in a subject, said method comprising quantitatively or qualitatively detecting the expression of cell surface marker CD25 and one or more of cell surface ...
Mechanistic studies revealed that autocrine IFN-α/β upregulated TRAIL expression on activated T cells to elicit MDSC apoptosis via the TRAIL–DR5 interaction and acted synergistically with TNF-α to inhibit MDSC function of suppressing the T-cell response through the JNK-NMDAR-ARG-1 pathway. ...
Human class-I restricted T cell associated molecule is highly expressed in the cerebellum and is a marker for activated NKT and CD8+ T lymphocytes. Genaro Patin?o-Lopez,Peter Hevezi,Jerry Lee,Dorian Willhite,Gail M Verge,Sandra M. Lechner,Vianney Ortiz-Navarrete,Albert Zlotnik. Journal de ...
This invention provides a monoclonal antibody which specifically recognizes and forms a complex with a protein located on the surface of activated T cells and thereby inhibits T cell activation of B cells. This invention also provides th... S Lederman,L Chess,MJ Yellin - US 被引量: 158发表:...
Marker of activation Storage Storage Buffer: PBS with 0.09% sodium azide. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. Usage Mouse Activated T Cell Panel Datasheet and User Guide Flow-Cytometry-Cell-Surface-Staining-Protocol Cited in Articl...
Cell-Surface Marker Signatures for the Isolation of Neural Stem Cells, Glia and Neurons Derived from Human Pluripotent Stem Cells identify cell-surface signatures that enable the isolation of these cell types from heterogeneous cell populations by fluorescence activated cell sorting (FACS)... SH Yuan...
Non-T cells in lesional skin also express these molecules. We quantitatively measured the number of T cells expressing cell surface activation-associated molecules (CD69, CD25, CD122, HLA-DR) and co-stimulatory molecules (CD28, CTLA-4, CD80, CD86), including a Type 2 T cell marker (CD30...
Sorted cells from the FUCCI-Red mice were then plated under adherent conditions to visualize the cell-cycle pt(oFhi7ags..3 e3 s±Ea) 0t. A.a3gshianoingu,lrens-ocaetdl2ilflfaeenrvedenl6.cAemwsopanestcohibsfi,screeGrsv1peledecnbtigevttewhleyene(niFnitggh.we 3EaCsG,FoFb...