Activated CD4+ T Cells impact adipose-serived stromal cell function through CD40-dependant activation - ScienceDirectBackground & Aim Although native bone marrow-derived mesenchymal stromal cells (BM-MSC) have been described to express CD40, how CD40 is regulated on MSC, and whether CD40 signaling...
Presensitization of tumor cells with aCD4 greatly increased tumor cell growth inhibition. Soluble factors secreted from activated CD4+ T cells were primarily responsible for the observed effect. IFN-γ seemed to play a major role. TNF-α, though inactive by itself, significantly augmented the radio...
co-culture with activated CD4+T cells resulted in a remarkable suppression of double positive (DP) cell production, which was accompanied by proportional increases of CD4 and CD8 SP cells (Fig.1b, upper andc). Among the DN thymocytes
Because naïve T cells are unable to import cystine due to the absence of cystine transporters, it has been suggested that T cell activation is dependent on cysteine generated by antigen presenting cells. The aim of this study was to determine at which phases during T cell activation exogenous...
Loss of activated CD4 T cells was independent of early instructional programming, T cell precursor frequency, and Ag availability. In contrast, apoptosis of Ag-specific CD4 T cells was actively induced by live bacteria in a process that required Salmonella pathogenicity island-2 and correlated with...
BACKGROUND: Methylprednisolone (MP) can affect the survival of CD4 + T lymphocytes and plays an important role in adaptive immune responses; however, its mechanism of action is not clear. Recent studies have shown that toll- like receptors (TLRs) on CD4 + T cells can directly modulate adaptiv...
,Schuler,T. 展开 摘要: Examines the sexual transmission of simian immunodeficiency virus (SIV) and human immunodeficiency virus-type 1 (HIV-1) infection in resting and activated CD4+ T cells. Identification of the types of cells in which SIV first replicates; Details on the cell cycle of ...
In the present study, we investigated the effect of interferona (IFN-a) on the expression of interleukin-10 (IL-10) mRNA and protein synthesis in human monocytes and CD4+ T cells. In mononuclear cells, IFN-a induced expression of IL-10 mRNA and further enhanced lipopolysaccharide (LPS)-sti...
Objective To study the relationship between the levels of T helper cells, natural killer T cells(NKT cell)natural killer cells(NK cell), and the developmen... LI Lijuan - 《China Medical Herald》 被引量: 0发表: 2019年 Discordance in CD4+T-Cell Levels and Viral Loads with Co-Occurrence ...
The responding cells bear Vγ9+ chains of the T cell receptor, the majority of which, but not all, are associated with V γ 2 chains. We have analyze... M Goodier,M Krause-Jauer,J Langhorne - 《European Journal of Immunology》 被引量: 41发表: 1992年 Detection of CD4+CD45RO+T ...