Wang Y,Radfar S,Khong HT.Activated CD4+T cells enhance radiation effect through the cooperation of interferon-r and TNF-a. BMC Cancer . 2010Wang Y,Radfar S,Khong HT.Activated CD4+T cells enhance radiation effect through the cooperation of interferon-r and TNF-a. BMC Cancer . 2010...
Approaches that enhance radiation effect may lead to improved clinical outcome and decrease toxicity. Here we investigated whether activated CD4+ T cells (aCD4) can serve as an effective radiosensitizer. CD4+ T cells were activated with anti-CD3 and anti
Next, ASC isolated by adhesion in culture were submitted to various stimuli or co-culture with activated CD4 T cells. Changes in gene expression and secretion profiles were studied by Q-PCR and ELISA. Neutrophil migration was measured through Transwell and involvement of the candidate pathways was...
Using fetal thymic organ cultures (FTOCs), the present study investigated the impact of recirculating T cells on the two major cell populations in the thymus, namely the thymocytes and the TECs. Co-culturing with activated T cells, especially CD4+T cells, had a significant inhibitory effect on...
Because naïve T cells are unable to import cystine due to the absence of cystine transporters, it has been suggested that T cell activation is dependent on cysteine generated by antigen presenting cells. The aim of this study was to determine at which phases during T cell activation exogenous...
Early appearance of activated CD4+ T lymphocytes and class II antigen-expressing cells in joints of DBA/1 mice immunized with type II collagen. Lab Invest 1988; 58:53±60.Holmdahl R, Jonsson R, Larsson P, Klareskog L: Early ... R Holmdahl - 《Laboratory Investigation》 被引量: 213发表...
Activated CD4 专利名称:Activated CD4 ▲ above + ▼ T cell ligand for a receptor on the surface of (ACT-4-L)发明人:ゴッドフライ,ウェイン,アングルマン,エドガージョージ 申请号:JP1995521040 申请日:19950206 公开号:JP3703834B2 公开日:20051005 专利内容由知识产权出版社提供 摘要: ...
Resting and activated human CD4+ T cells express functional 5-HT3 receptor.Elena MagriniIldikò SzabòAndrea DoniJavier CibellaAntonella Viola
Resting and activated human CD4+ T cells express functional 5-HT3 receptor. E Magrini,I Szabò,A Doni,... 被引量: 0发表: 2013年 5-HT3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line. Serotonin (5-HT) induces a large inward current accompanied by a ...
T cell-mediated responses have been implicated in the development of fibrosis, impaired lymphangiogenesis, and lymphatic dysfunction in secondary lymphedema. Here we show that CD4+ T cells are necessary for lymphedema pathogenesis by utilizing adopt