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Thyroid hormones are known to stimulate in vivo the synthesis of several liver proteins. In order to determine their role in the regulation of important hepatic proteins at the cell level, the effect of T3 on the induction of the glucoregulatory enzyme phosphoenol pyruvate carboxykinase (PEPck) ...
The skin characteristics associated with thyroid hormone are classic. The name "myxedema," refers to the associated skin condition caused by increased glycosaminoglycan deposition in the skin. Generalized myxedema is still the classic cutaneous sign of hypothyroidism. It is caused by deposition of ...
1. Action of specific thyroid hormone receptor α1 and β1 antagonists in the central and peripheral regulation of thyroid hormone metabolism in the rat [J] . Thyroid: official journal of the American Thyroid Association . 2012,第12期 机译:特定甲状腺激素受体α1和β1拮抗剂在大鼠甲状腺激素代...
Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid hormones potentiate both the antiviral and immunomodulatory actions of IFNγ i
A. Structure of human chorionic gonadotropin at 2.6 Å resolution from MAD analysis of the selenomethionyl protein. Structure 2, 545–558 (1994). Article CAS PubMed Google Scholar Grossmann, M. et al. Substitution of the seat-belt region of the thyroid-stimulating hormone (TSH) β-...
The major biologically active thyroid hormone 3,5,3'-triiodothyronine (T 3 ) exerts effects upon almost every cell and tissue of the body influencing function, as well as in many cases the growth and development of that tissue. T 3 is known to regulate the level of expression of a large...
Previously we demonstrated the stimulation of collagen synthesis in triiodothyroacetic acid (TRIAC)-topically treated human and mice. In the present study, we have evaluated the dose response effect of thyroid hormone (TH) analogues and tretinoin on glucocorticoid-induced skin atrophy in a haired mou...
Ribonucleic acid synthesis during the early action of thyroid hormones 1. The effect on RNA synthesis in rat liver of thyroidectomy and the administration of thyroid hormone, especially during its physiological latent period, ... JR Tata,CC Widnell - 《Biochemical Journal》...
Thyroid hormone (TH) plays an important role in the modulation of cardiac function, including contractility and systemic vascular resistance (SVR). 3,5,3'-triiodothyronine (T(3)), the active form of TH, induces the activation of endothelial nitric oxide synthase via PI3K/AKT non-genomic signali...