Dibutyryl 3',5'-AMP, an analogue of 3',5'-AMP, mimics some of the actions of thyroid-stimulating hormone (TSH) on the thyroid. Both substances increase glucose-1- 14 C oxidation to 14 CO 2 in the dog. Dibutyryl 3',5'-AMP is active over the range of 10 to 250 g per ml. ...
Thyrotropin-Releasing Hormone Action in Thyrotropic Cells: Mechanism of Stimulation of Thyroid-Stimulating Hormone SecretionProduction of pituitary thyrotropin (thyroid-stimulating hormone; TSH), the major modulator of secretion of L-triiodothyronine (L-T 3 ) and L-thyroxine (L-T 4 ) from the ...
In most iodine-proficient human populations without thyroid disease, the mean, median and 97.5 centile for circulating concentrations of thyroid-stimulating hormone are progressively higher in adults over 80 years of age compared with middle-aged (50–59 years) and younger (20–29 years) ...
TH action is mainly exerted by interaction with TH and thyroid hormone receptors (THRs) which are mainly of two types,THRαandTHRβ. THR is a nuclear receptor that requires TH as a ligand to be activated. THR binds to thyroid hormone response element (TRE) on the gene promoter and general...
common to TSH,luteinizing hormone(LH), follicle-stimulating hormone (FSH), andhuman chorionic gonadotropin, whereas the β subunit in each of these hormones is unique and confers specificity of action. Production of TSH is stimulated by thyrotropin-releasing hormone (TRH) and inhibited by...
Noun1.thyroid-stimulating hormone- anterior pituitary hormone that stimulates the function of the thyroid gland thyrotrophic hormone,thyrotrophin,thyrotropic hormone,thyrotropin,TSH endocrine,hormone,internal secretion- the secretion of an endocrine gland that is transmitted by the blood to the tissue on...
Evidence using mice lacking the thyroid hormone receptors α and β establishes a role for thyroid hormones in regulating bone remodeling but does not exclude an independent action of thyroid-stimulating hormone (TSH), levels of which are low in hyperthyroid states, even when thyroid hormones are ...
3.1. Early life stress transiently increases thyroid-stimulating hormone In order to determine whether and how long ELS disrupts thyroid hormone signaling, we examined thyroid-stimulating hormone (TSH) in males and females at three time points (Fig. 1A): P21 prior to weaning, P40 during adolescenc...
Synder PJ, Utiger RD: Response to thyrotropin releasing hormone (TRH) in normal man.J Clin Endocrinol Metab34: 380–385, 1972. Google Scholar Ramey JN, Burrow GN, Polackwich RJ, et al: The effect of oral contraceptive steroids on the response of thyroid stimulating hormone to thyrotropin-rel...
TSH Thyroid Stimulating Hormone References Mancino, G.; Miro, C.; Di Cicco, E.; Dentice, M. Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin. J. Endocrinol. Investig. 2021, 44, 1571–1579. [Google Scholar] [CrossRef] ...