optical activity [α]/D alpha: 28/D (Rotation: -315 degrees (c=0.25% in methanol)) biological source Streptomyces sp. Water Solubility SOLUBLE Merck 13,2828 BRN 605235 Stability Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, str...
Actinomycin D (ActD), cordycepin (COR), and cycloheximide (CHX) are used to analyze NMD. ActD and COR are transcription inhibitors that are used frequently for mRNA stability analysis. Act D binds to DNA so as to inhibit elongation executed by RNA polymerase. COR (3′-deoxyadenosine), which...
Further studies on the stability of total cellular RNA, where synthesis was depressed by Actinomycin D, indicated that very little degradation of this nucleic acid occurred following large doses of ionizing radiation. On the other hand, the stability of DNA in cells was affected in cells exposed...
摘要: Actinomycin D, in addition to preventing incorporation of uridine into cellular RNA, also prevents the "migration"of previously incorporated radioactive uridine in acid insoluble form from the nucleus to the cytoplasm of HeLa cells.关键词: ACTINOMYCIN CYTOLOGY EXPERIMENTAL LAB STUDY NEOPLASMS, ...
部份中文更生霉素放线菌素处方资料(仅供参考)英文名:Actinomycin D商品名:COSMEGEN IV Injection 0.5mg中文名:放线菌素D生产商:Nobel Pharma Corporation药物分类名称:抗肿瘤抗生素批准日期:2013年1月商品名:COSMEGEN IV Injection 0.5mg一般名:アクチノマイシンD (Actinomycin D)化学名:Specific stereoisomer of N...
RNA stability experiments using actinomycin D revealed that the half life of IL-6 mRNA (hours) was increased from 2.8 hours in control cells to 6.7 ... J Wowsk,A Jörrs,R Cos,... - 《Kidney International》 被引量: 205发表: 1996年 Efficacy of type-specific and cross-reactive murine...
药店国别:产地国家:日本处方药:所属类别:0.5毫克/瓶 1瓶包装规格:0.5毫克/瓶 1瓶计价单位:瓶生产厂家中文参考译名:生产厂家英文名:Nobel Pharma Corporation原产地英文商品名:COSMEGEN IV Injection(コスメゲン静注用)0.5MG/vial原产地英文药品名:Actinomycin D中文参考商品译名:COSMEGEN(コスメゲン静注用)0.5毫...
E. Smith, D. Neville, and G. Felsenfeld: Actinomycin binding to Dna; mechanism and specificity. J. Mol. Biol. 11, 445 (1965). Article PubMed CAS Google Scholar Goldberg, I. H., and E. Reich: Actinomycin inhibition of Rna synthesis directed by Dna. Federation Proc. 23, 958 (1964...
It is suggested that the differential susceptibility of these cell types to acute poisoning by AMD may reflect differences among various cells in the function or stability of certain RNA species not directly involved in translation whose presence is vital to cells. In HeLa cells, these critical ...
Product Name Actinomycin / Dactinomycin Synonym Actinomyucin D; Meractinomycin Formula Wt. 1255.41 Melting Point 243oC-248oC(dec.) Purity ≥98% Solubility Soluble in ethanol, propylene glycol, water + glycol mixture, or DMSO. Stability 2 years at 4 oC. Store Temp +4oC Ship Tem...