Actin remodeling contributing to cell migration is a coordinated process involving the severing of existing filaments to generate new barbed ends, the action of actin capping proteins to restrict polymerization, the branching mediated by Arp2/3, and the bundling and cross-linking of actin filaments....
Actin remodeling by ADF/cofilin is required for cargo sorting at the trans-Golgi network. J. Cell Biol. 2009;187(7):1055-69.von Blume, J., Duran, J. M., Forlanelli, E., Alleaume, A.-M., Egorov, M., Polishchuk, R., Molina, H. and Malhotra, V. (2009). Actin remodeling ...
2021年11月2日,南洋理工大学缪岩松课题组与福建农林大学和南方科技大学合作在Plant Cell杂志发表了题为“Membrane nanodomains modulate formin condensation for actin remodeling in Arabidopsis innate immune responses”的研究论文,揭示了植物通过remorin蛋白促进formin蛋白在细胞膜的分子聚集影响拟南芥先天免疫反应的肌动蛋...
Actin remodeling is the result of activation of oncogenic actin signaling pathways (e.g., Ras and Src), or inactivation of several important actin-binding proteins that have tumor suppressor functions (e.g., gelsolin). Distinctive protein expression patterns of some of these genes in cancer and...
remodeling has been shown to be crucial for the regulation of vesicular trafficking and hormone secretion.7,23 To investigate the possibility that actin remodeling is involved in AMPK- dependent KATP channel trafficking in pancreatic β-cells, we first examined whether GD induces actin remodeling. INS...
Here we investigate the role of the Actin cytoskeleton in the formation of the Drosophila compound eye, which requires extensive remodeling and coordination between different cell types. We show that CYFIP/Sra-1, a member of the WAVE/SCAR complex and regulator of Actin remodeling, controls ...
The regulation of actin remodeling during T-cell–APC conjugate formation Summary: The T-cell cytoskeleton is intimately involved in determining the efficiency and fidelity of the immune response. During T-cell interactions with ... JL Cannon,JK Burkhardt - 《Immunological Reviews》 被引量: 190发表...
In the present study, we demonstrate that changes in adipocyte size correlate with a drastic remodeling of the actin cytoskeleton. Expansion of primary adipocytes following 2 weeks of high-fat diet (HFD)-feeding in C57BL6/J mice was associated with a drastic increase in filamentous (F)-actin ...
www.mdpi.com/journal/ijms WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions 来自 Citeseer 喜欢 0 阅读量: 50 作者:E Noy,S Fried,O Matalon,M Bardasaad 摘要: Actin polymerization is a fundamental cellular process regulating immune cell functions and the immune ...
The remodeling of actin networks is required for a variety of cellular processes in eukaryotes. In plants, several actin binding proteins have been implicated in remodeling cortical actin filaments (F-actin). However, the extent to which these proteins support F-actin dynamics in planta has not ...