Despite the recognized importance of actin-binding protein Flightless-1 (FLII) during actin remodeling, the role played by FLII in the differentiation of myogenic progenitor cells has not been explored. Here, we investigated the roles of FLII in the proliferation and differentiation of myoblasts. ...
FLII is a member of the actin-remodelling gelsolin protein superfamily and has been implicated in cell migration. It has been shown to translocate from the nucleus and perinuclear region in motile NIH3T3 cells to actin-rich regions at the cell periphery, including membrane ruffles and the leading...
FLII is a member of the actin-remodelling gelsolin protein superfamily and has been implicated in cell migration. It has been shown to translocate from the nucleus and perinuclear region in motile NIH3T3 cells to actin-rich regions at the cell periphery, including membrane ruffles and the leading...