PURPOSE:To obtain an acid amide useful as a solvent, plasticizer, dye, agricultural chemical, pharmaceutical, etc., or their synthetic intermediate, in high yield and purity while suppressing the production of by-product, by reacting a carboxylic acid with an amine in liquid or vapor phase in ...
SYNTHESIS OF ACID AMIDE 来自 百度文库 喜欢 0 阅读量: 10 申请(专利)号: JP19860072568 申请日期: 1986-04-01 公开/公告号: JPH0465058B2 公开/公告日期: 1992-10-16 申请(专利权)人: NIPPON TOBACCO SANGYO 发明人:M Hajime,S Makoto,T Kyoko 摘要: A process of synthesizing carboxylic acid amide ...
Amide 酰胺 -amide 酰胺 Amidine 脒 -amidine 脒 Aminal 缩醛胺 Amine oxide 氧化胺 Amine 胺 -amine 胺 Amino acid 氨基酸 amino- 氨基的 -ane 烷 anhydride 酐 anilino- 苯胺基 aquo- 含水的 -ase 酶 -ate 含氧酸的盐、酯 -atriyne 三炔 Azine 嗪 azo- 偶氮 benzene 苯 Betaine 甜菜碱 bi- 在盐...
We recently reported molecules designed according to the multitarget-directed ligand paradigm to exert combined activity at human fatty acid amide hydrolase (FAAH) and dopamine receptor subtype D3 (D3R). Both targets are relevant for tackling several types of addiction (most notably nicotine addictio...
Further support for this head-to-tail arrangement was obtained in hybridization experiments.91 In these experiments, the pantetheine-SH group was chemically modified with chloroacetyl-CoA and the cysteine-SH group with iodoacetoamide. The resulting enzyme variants were dissociated and hybridized. The ...
diol-esters formed in the unsaturated diols, and esterfication of the diol-esters with sulfated chains with or without and amide function in the DTX-4 and DTX-5a-c groups) and other compounds that comprise changes to the OA backbone (e.g., norokadanone, 19-epi-OA, and belizeanic acid...
Synthesis of Oligomers Derived from Amide-Linked Neuraminic Acid Analogues # N -Fluoren-9-ylmethoxycarbonyl-protected sugar amino acids derived from α- O -methoxy- and 2,3-dehydroneuraminic acids have been prepared. Incorporation o... 被引量: 0发表: 2003年 Molecular Modeling Studies on Ligand...
Synthesis and Biological Evaluation of Triazol-4-ylphenyl-Bearing Histone Deacetylase Inhibitors as Anticancer Agents Our triazole-based histone deacetylase inhibitor (HDACI), octanedioic acid hydroxyamide[3-(1-phenyl-1H-[1,2,3]triazol-4-yl)phenyl]amide (4a), suppresses pa... R He,Y Chen,Y...
to form a disulfide bond through intra- or intermolecular interactions. Thiol-based reductants, including Trx and GSH, can reduce disulfide bonds via the thiol disulfide exchange reaction. The sulfur atom in sulfenic acid can also react with amide nitrogen within a given protein to form a cyclic...
In astrocytoma, PSA expression is also associated with higher grade and the fraction of cells expressing PSA is 10-fold higher in WHO grade III and IV (GBM) tumors as compared to WHO grade II tumors (Petridis et al., 2009). PSA synthesis is governed by two glycosyltransferases, ST8 α-...