1985. Acetylcholine receptor structure, function, and evolution. Annual Review of Cell Biology. 1:317-351.Lindstrom J. Acetylcholine receptor structure. In: Kaminski HJ, ed. Myasthenia Gravis and Related Disorders. Totowa, NJ: Humana Press; 2003:15-52...
Over the past decade, studies of the atomic structure and the structural mechanism of nicotinic acetylcholine receptor (AChR) gating have reached an advanced stage. AChRs are members and prototypes of the superfamily of Cys-loop pentameric ligand-gated ion channels. AChRs are expressed by neurons ...
The structure, function, and physiology of the fetal and adult acetylcholine receptor in muscle. Front. Mol. Neurosci. 13, 581097 (2020). CAS PubMed PubMed Central Google Scholar Rimer, M., Mathiesen, I., Lømo, T. & McMahan, U. J. γ-AChR/ε-AChR switch at agrin-induced ...
Nicotinic Acetylcholine Receptors: From Structure to Brain Function.- Cytochrome c Oxidase Structure, Function, and Physiology of a Redox-Driven Molecular ... E Helmreich - Springer Berlin Heidelberg 被引量: 0发表: 1981年 Functional Architecture of the Nicotinic Acetylcholine Receptor: From Electric Or...
Structure and function of an acetylcholine receptor. Structural analysis of an acetylcholine receptor from Torpedo californica leads to a three-dimensional model in which a "monomeric" receptor is shown to contain subunits arranged around a central ionophoretic channel, which in turn trave... J ...
CARROLL, R. C., M. E. ELDEFRAWI, and S. J. EDELSTEIN. 1973. Studies on the structure of the acetylcholine receptor from Torpedo marmorata. Biochem. Biophys. Res., Commun. 55:864-872.Carroll , R. , Eldefrawi , M. , and Edelstein , S. , 1973, Studies on the structure of the...
The X-ray crystal structure of the M3 muscarinic acetylcholine receptor bound to the bronchodilator drug tiotropium is reported; comparison of this structure with that of the M2 muscarinic acetylcholine receptor reveals key differences that could potenti
The conversion of acetylcholine binding into ion conduction across the membrane is becoming more clearly understood in terms of the structure of the receptor and its transitions. A high-resolution structure of a protein that is homologous to the extracellular domain of the receptor has revealed the ...
Muscarinic acetylcholine receptor subtypes: localization and structure/function. V. (1993) Muscarinic acetylcholine receptor subtypes: localization and structure/function. Prog. Brain Res. 9, 121-127.Brann MR, Ellis J, Jorgensen H,... MR Brann,J Ellis,H Jørgensen,... - Peter Lang, 被引量:...
Mechanistic Insights into Allosteric Structure-Function Relationships at the M1 Muscarinic Acetylcholine Receptor Benzylquinolone carboxylic acid (BQCA) is the first highly selective positive allosteric modulator (PAM) for the M1 muscarinic acetylcholine receptor (mACh... A Abdul-Ridha,JR Lane,SN Mistry...